3ZDW

Substrate and dioxygen binding to the endospore coat laccase CotA from Bacillus subtilis

Replaces:  1UVW

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0030435	biological_process	sporulation resulting in formation of a cellular spore
A	0046872	molecular_function	metal ion binding
A	0047705	molecular_function	bilirubin oxidase activity
A	0052716	molecular_function	hydroquinone:oxygen oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU1 A 1511

Chain	Residue
A	HIS419
A	CYS492
A	HIS497
A	MET502

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU1 A 1512

Chain	Residue
A	HIS107
A	HIS153
A	HIS493
A	OXY1515

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU1 A 1513

Chain	Residue
A	HIS424
A	HIS491
A	CU11514
A	OXY1515
A	HIS155

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CU1 A 1514

Chain	Residue
A	HIS105
A	HIS107
A	HIS422
A	HIS424
A	CU11513
A	OXY1515
A	HOH2056

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE OXY A 1515

Chain	Residue
A	HIS105
A	HIS107
A	HIS153
A	HIS155
A	HIS422
A	HIS424
A	HIS491
A	HIS493
A	CU11512
A	CU11513
A	CU11514
A	HOH2093

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EBS A 1516

Chain	Residue
A	PRO226
A	ALA227
A	CYS229
A	GLY323
A	PRO384
A	HIS497

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1519

Chain	Residue
A	ASP113
A	ASP114
A	TYR133
A	LYS135
A	ARG487
A	HOH2062
A	HOH2064

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1520

Chain	Residue
A	ARG136
A	GLU137
A	VAL138
A	PRO247
A	THR307
A	GLU310
A	GOL1524

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1521

Chain	Residue
A	GLN20
A	LYS25
A	VAL138
A	ALA308
A	GLU310
A	GOL1524

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1522

Chain	Residue
A	PRO112
A	ASP113
A	TYR484
A	SER485
A	TYR488
A	HOH2069

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1523

Chain	Residue
A	GLU128
A	ILE369
A	THR371
A	SER410
A	ARG476
A	GOL1525

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1524

Chain	Residue
A	VAL138
A	THR307
A	ALA308
A	TYR309
A	GLU310
A	GOL1520
A	GOL1521

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 1525

Chain	Residue
A	LEU447
A	GOL1523

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Domain: {"description":"Plastocyanin-like 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	77
Details	Domain: {"description":"Plastocyanin-like 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	78
Details	Domain: {"description":"Plastocyanin-like 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	131
Details	Domain: {"description":"Plastocyanin-like 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"description":"type 2 copper site","evidences":[{"source":"PubMed","id":"12637519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14764581","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16234932","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20822511","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GSK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OF0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W8E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZDW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"description":"type 3 copper site","evidences":[{"source":"PubMed","id":"12637519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14764581","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16234932","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20822511","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27050268","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GSK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OF0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W8E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"description":"type 1 copper site","evidences":[{"source":"PubMed","id":"12637519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14764581","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16234932","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20822511","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27050268","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GSK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OF0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W8E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"description":"type 1 copper site","evidences":[{"source":"PubMed","id":"12637519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16234932","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20822511","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27050268","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GSK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OF0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W8E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YVU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Site: {"description":"Plays a crucial role in the protonation steps","evidences":[{"source":"PubMed","id":"22481612","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Site: {"description":"Plays a crucial role in the protonation steps","evidences":[{"source":"PubMed","id":"20200715","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20822511","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22481612","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---