3ZDF
Structure of GAPDH with CP12 peptide from Thermosynechococcus elongatus
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
A | 0006006 | biological_process | glucose metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
A | 0046872 | molecular_function | metal ion binding |
A | 0050661 | molecular_function | NADP binding |
A | 0051287 | molecular_function | NAD binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
B | 0006006 | biological_process | glucose metabolic process |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
B | 0046872 | molecular_function | metal ion binding |
B | 0050661 | molecular_function | NADP binding |
B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 28 |
Details | BINDING SITE FOR RESIDUE NAD A 1001 |
Chain | Residue |
A | GLY8 |
A | ALA99 |
A | THR100 |
A | GLY101 |
A | PHE103 |
A | THR123 |
A | ALA124 |
A | CYS154 |
A | ASN317 |
A | TYR321 |
A | HOH2001 |
A | PHE9 |
A | HOH2002 |
A | HOH2003 |
A | HOH2033 |
A | HOH2067 |
A | HOH2070 |
B | HOH2037 |
D | ASP66 |
D | ARG71 |
D | TYR73 |
A | GLY10 |
A | ARG11 |
A | ILE12 |
A | ASN35 |
A | ASP36 |
A | THR37 |
A | ARG81 |
site_id | AC2 |
Number of Residues | 30 |
Details | BINDING SITE FOR RESIDUE NAD B 1001 |
Chain | Residue |
A | HOH2038 |
A | HOH2039 |
B | GLY8 |
B | PHE9 |
B | GLY10 |
B | ARG11 |
B | ILE12 |
B | ASN35 |
B | ASP36 |
B | THR37 |
B | ARG81 |
B | ALA99 |
B | THR100 |
B | GLY101 |
B | PHE103 |
B | THR123 |
B | ALA124 |
B | CYS154 |
B | ASN317 |
B | TYR321 |
B | HOH2002 |
B | HOH2003 |
B | HOH2029 |
B | HOH2065 |
B | HOH2068 |
B | HOH2069 |
B | HOH2070 |
C | ASP66 |
C | ARG71 |
C | TYR73 |
Functional Information from PROSITE/UniProt
site_id | PS00071 |
Number of Residues | 8 |
Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
Chain | Residue | Details |
A | ALA152-LEU159 |