3X0E

Crystal structure of the ectodomain of human CD81 large extracellular loop (hCD81-LEL)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	GLN133
A	ALA140
A	ASN142
A	ALA143
A	HOH444
A	HOH452

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 302

Chain	Residue
A	HOH410

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 303

Chain	Residue
A	ASN142
A	ALA143

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 301

Chain	Residue
B	LYS201
B	HOH440

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 302

Chain	Residue
A	ASN141
A	HOH457
B	HOH446
B	HOH452

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	176
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:27881302

Chain	Residue	Details
A	PHE113-LYS201
B	PHE113-LYS201

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site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Important for interaction with integrin => ECO:0000269|PubMed:27993971

Chain	Residue	Details
A	LYS116
A	LYS144
A	LYS148
B	LYS116
B	LYS144
B	LYS148

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