3WYC
Structure of a meso-diaminopimelate dehydrogenase in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0047850 | molecular_function | diaminopimelate dehydrogenase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0047850 | molecular_function | diaminopimelate dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAP A 1001 |
| Chain | Residue |
| A | GLY10 |
| A | GLY70 |
| A | GLY71 |
| A | SER72 |
| A | ASP75 |
| A | SER92 |
| A | ASP94 |
| A | VAL121 |
| A | TRP123 |
| A | ASP124 |
| A | PRO125 |
| A | TYR11 |
| A | ASN276 |
| A | THR280 |
| A | NES1002 |
| A | HOH1107 |
| A | HOH1113 |
| A | HOH1115 |
| A | HOH1120 |
| A | HOH1125 |
| A | HOH1137 |
| A | HOH1142 |
| A | GLY12 |
| A | HOH1147 |
| A | HOH1173 |
| A | HOH1204 |
| A | HOH1236 |
| A | HOH1272 |
| A | HOH1275 |
| B | LYS213 |
| A | ASN13 |
| A | LEU14 |
| A | THR35 |
| A | ARG36 |
| A | ARG37 |
| A | CYS69 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE NES A 1002 |
| Chain | Residue |
| A | TRP123 |
| A | ASP124 |
| A | TRP148 |
| A | SER153 |
| A | HIS156 |
| A | THR173 |
| A | ARG199 |
| A | HIS249 |
| A | NAP1001 |
| A | HOH1139 |
| A | HOH1183 |
| A | HOH1239 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NES A 1003 |
| Chain | Residue |
| A | VAL53 |
| A | ASP54 |
| A | GLU78 |
| A | GLN79 |
| A | TYR82 |
| A | HOH1228 |
| site_id | AC4 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAP B 1001 |
| Chain | Residue |
| A | LYS213 |
| B | GLY10 |
| B | TYR11 |
| B | GLY12 |
| B | ASN13 |
| B | LEU14 |
| B | THR35 |
| B | ARG36 |
| B | ARG37 |
| B | CYS69 |
| B | GLY70 |
| B | GLY71 |
| B | SER72 |
| B | ASP75 |
| B | SER92 |
| B | ASP94 |
| B | VAL121 |
| B | TRP123 |
| B | ASP124 |
| B | PRO125 |
| B | ASN276 |
| B | THR280 |
| B | NES1002 |
| B | HOH1104 |
| B | HOH1112 |
| B | HOH1115 |
| B | HOH1121 |
| B | HOH1131 |
| B | HOH1133 |
| B | HOH1137 |
| B | HOH1225 |
| B | HOH1232 |
| B | HOH1234 |
| B | HOH1251 |
| B | HOH1252 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NES B 1002 |
| Chain | Residue |
| B | HOH1227 |
| B | TRP123 |
| B | ASP124 |
| B | TRP148 |
| B | SER153 |
| B | HIS156 |
| B | THR173 |
| B | ARG199 |
| B | HIS249 |
| B | NAP1001 |
| B | HOH1147 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NES B 1003 |
| Chain | Residue |
| B | VAL53 |
| B | ASP54 |
| B | GLU78 |
| B | GLN79 |
| B | TYR82 |
| B | PHE83 |
| B | HOH1207 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
