3WY0
The I375W mutant of CsyB complexed with CoA-SH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016210 | molecular_function | naringenin-chalcone synthase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030639 | biological_process | polyketide biosynthetic process |
| A | 0034083 | cellular_component | type III polyketide synthase complex |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0090439 | molecular_function | tetraketide alpha-pyrone synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016210 | molecular_function | naringenin-chalcone synthase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030639 | biological_process | polyketide biosynthetic process |
| B | 0034083 | cellular_component | type III polyketide synthase complex |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0090439 | molecular_function | tetraketide alpha-pyrone synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE COA A 401 |
| Chain | Residue |
| A | LYS50 |
| A | ILE271 |
| A | GLY312 |
| A | GLY313 |
| A | TYR314 |
| A | ALA315 |
| A | HOH531 |
| A | HOH563 |
| A | HOH604 |
| A | HOH677 |
| A | HOH714 |
| A | ILE54 |
| A | HOH773 |
| A | LYS57 |
| A | THR58 |
| A | ARG59 |
| A | VAL208 |
| A | LEU212 |
| A | ILE267 |
| A | LYS269 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE COA B 401 |
| Chain | Residue |
| B | LYS50 |
| B | ILE54 |
| B | LYS57 |
| B | THR58 |
| B | VAL208 |
| B | LEU212 |
| B | ILE267 |
| B | LYS269 |
| B | ILE271 |
| B | GLY312 |
| B | GLY313 |
| B | TYR314 |
| B | ALA315 |
| B | HOH545 |
| B | HOH561 |
| B | HOH622 |
| B | HOH644 |
| B | HOH675 |
| B | HOH730 |
| B | HOH756 |
| B | HOH768 |
| B | HOH780 |
| B | HOH821 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10023, ECO:0000269|PubMed:25564614 |
| Chain | Residue | Details |
| A | CYS155 | |
| B | CYS155 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:25564614 |
| Chain | Residue | Details |
| A | HIS377 | |
| B | HIS377 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25564614, ECO:0007744|PDB:3WXY |
| Chain | Residue | Details |
| A | LYS50 | |
| B | ALA315 | |
| A | ILE267 | |
| A | GLY312 | |
| A | TYR314 | |
| A | ALA315 | |
| B | LYS50 | |
| B | ILE267 | |
| B | GLY312 | |
| B | TYR314 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P30074 |
| Chain | Residue | Details |
| A | GLY214 | |
| B | GLY214 |
