3WWR
Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1-((((1S,2R,6R,Z)-2,6-dihydroxy-4-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-3-methylenecyclohexyl)oxy)methyl)cyclopropanecarbonitrile
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0004879 | molecular_function | nuclear receptor activity |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE 3AJ A 501 |
Chain | Residue |
A | TYR143 |
A | CYS288 |
A | HIS305 |
A | HIS397 |
A | ASP144 |
A | LEU227 |
A | VAL234 |
A | SER237 |
A | ILE271 |
A | ARG274 |
A | SER275 |
A | SER278 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR143 | |
A | ARG274 | |
Chain | Residue | Details |
A | SER237 | |
Chain | Residue | Details |
A | SER278 | |
A | HIS305 | |
Chain | Residue | Details |
A | HIS397 | |