3WWR
Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1-((((1S,2R,6R,Z)-2,6-dihydroxy-4-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-3-methylenecyclohexyl)oxy)methyl)cyclopropanecarbonitrile
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 3AJ A 501 |
| Chain | Residue |
| A | TYR143 |
| A | CYS288 |
| A | HIS305 |
| A | HIS397 |
| A | ASP144 |
| A | LEU227 |
| A | VAL234 |
| A | SER237 |
| A | ILE271 |
| A | ARG274 |
| A | SER275 |
| A | SER278 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS305 | |
| A | HIS397 | |
| A | TYR143 | |
| A | LEU227 | |
| A | ILE271 | |
