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3WW0

Crystal structure of F97A mutant, a new nuclear transport receptor of Hsp70

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006606biological_processprotein import into nucleus
A0015031biological_processprotein transport
A0030544molecular_functionHsp70 protein binding
A0034605biological_processcellular response to heat
A0061608molecular_functionnuclear import signal receptor activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006606biological_processprotein import into nucleus
B0015031biological_processprotein transport
B0030544molecular_functionHsp70 protein binding
B0034605biological_processcellular response to heat
B0061608molecular_functionnuclear import signal receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues74
DetailsRegion: {"description":"Required for F-X-F-G repeats-nucleoporins recognition and nuclear import","evidences":[{"source":"PubMed","id":"22541429","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues20
DetailsRegion: {"description":"Flexible linker region involved in nuclear import of HSP70 proteins","evidences":[{"source":"PubMed","id":"22541429","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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