3WQB
Crystal structure of aeromonas sobria serine protease (ASP) and the chaperone (ORF2) complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0016020 | cellular_component | membrane |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 901 |
| Chain | Residue |
| A | ASN29 |
| A | ASP87 |
| A | VAL126 |
| A | ASN128 |
| A | ILE130 |
| A | THR132 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 902 |
| Chain | Residue |
| A | ALA555 |
| A | ASN578 |
| A | ASN579 |
| A | ASP454 |
| A | ASP488 |
| A | ASP553 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 903 |
| Chain | Residue |
| A | ASP297 |
| A | LEU298 |
| A | GLY300 |
| A | MET303 |
| A | ASN306 |
| A | CYS326 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVVDDGLaiaH |
| Chain | Residue | Details |
| A | VAL74-HIS85 |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGTsVSGiIAA |
| Chain | Residue | Details |
| A | HIS115-ALA125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 362 |
| Details | Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19654332","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25784551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HJR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WQB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
