Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEB A 801 |
| Chain | Residue |
| A | GLY87 |
| A | HIS263 |
| A | GLY266 |
| A | LYS267 |
| A | CYS268 |
| A | HIS269 |
| A | THR307 |
| A | SER308 |
| A | TRP314 |
| A | TRP406 |
| A | HOH915 |
| A | LEU88 |
| A | HOH943 |
| A | HOH978 |
| A | ILE90 |
| A | ARG91 |
| A | TRP94 |
| A | PHE245 |
| A | LEU258 |
| A | THR259 |
| A | GLY262 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 802 |
| Chain | Residue |
| A | GLY105 |
| A | ARG106 |
| A | GLY107 |
| A | SER476 |
| A | HOH1078 |
| A | HOH1325 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 803 |
| Chain | Residue |
| A | THR264 |
| A | THR315 |
| A | HIS317 |
| A | GLN320 |
| A | ASP322 |
Functional Information from PROSITE/UniProt
| site_id | PS00436 |
| Number of Residues | 12 |
| Details | PEROXIDASE_2 Peroxidases active site signature. GGlmIRLtWHAA |
| Chain | Residue | Details |
| A | GLY86-ALA97 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-248)"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-94)"} |
