3WID
Structure of a glucose dehydrogenase T277F mutant in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005536 | molecular_function | D-glucose binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| A | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| A | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| A | 0070401 | molecular_function | NADP+ binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005536 | molecular_function | D-glucose binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| B | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| B | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| B | 0070401 | molecular_function | NADP+ binding |
| B | 0070403 | molecular_function | NAD+ binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005536 | molecular_function | D-glucose binding |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| C | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| C | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| C | 0070401 | molecular_function | NADP+ binding |
| C | 0070403 | molecular_function | NAD+ binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005536 | molecular_function | D-glucose binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| D | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| D | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| D | 0070401 | molecular_function | NADP+ binding |
| D | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1001 |
| Chain | Residue |
| A | CYS99 |
| A | CYS102 |
| A | CYS110 |
| A | ASP116 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAP A 1002 |
| Chain | Residue |
| A | ASN216 |
| A | ARG217 |
| A | HIS218 |
| A | TYR238 |
| A | THR252 |
| A | SER253 |
| A | ASP255 |
| A | THR258 |
| A | PHE275 |
| A | GLY276 |
| A | PHE277 |
| A | SER304 |
| A | VAL305 |
| A | ASP306 |
| A | HOH1127 |
| A | HOH1147 |
| A | HOH1167 |
| C | VAL295 |
| A | ILE192 |
| A | SER194 |
| A | GLY195 |
| A | SER196 |
| A | GLU197 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGO A 1003 |
| Chain | Residue |
| A | ARG95 |
| A | LEU125 |
| A | HIS126 |
| A | ARG130 |
| A | TYR134 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1PE A 1004 |
| Chain | Residue |
| A | TYR82 |
| A | ILE137 |
| A | LEU140 |
| A | VAL141 |
| A | LYS142 |
| A | LYS309 |
| A | VAL313 |
| B | ASP181 |
| B | ILE185 |
| B | GLY209 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 1PE B 4001 |
| Chain | Residue |
| A | ARG106 |
| A | HOH1115 |
| B | LYS173 |
| B | GLN178 |
| B | SER182 |
| C | LYS173 |
| C | ARG174 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 4002 |
| Chain | Residue |
| B | CYS99 |
| B | CYS102 |
| B | CYS110 |
| B | ASP116 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAP B 4003 |
| Chain | Residue |
| B | ILE192 |
| B | SER194 |
| B | GLY195 |
| B | SER196 |
| B | GLU197 |
| B | ASN216 |
| B | ARG217 |
| B | HIS218 |
| B | TYR238 |
| B | THR252 |
| B | ASP255 |
| B | THR258 |
| B | PHE275 |
| B | PHE277 |
| B | SER304 |
| B | VAL305 |
| B | ASP306 |
| B | HOH4125 |
| B | HOH4129 |
| B | HOH4197 |
| D | VAL295 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO B 4004 |
| Chain | Residue |
| B | ARG95 |
| B | ALA120 |
| B | HIS126 |
| B | ARG130 |
| B | TYR134 |
| B | HOH4170 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PE B 4005 |
| Chain | Residue |
| A | GLN178 |
| A | SER182 |
| B | ARG106 |
| B | GLU166 |
| B | HIS311 |
| B | GLN314 |
| B | HOH4119 |
| B | HOH4200 |
| D | ARG174 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 1PE B 4006 |
| Chain | Residue |
| B | ASP317 |
| B | HOH4145 |
| A | ASP181 |
| A | ILE185 |
| B | ILE137 |
| B | LEU140 |
| B | VAL141 |
| B | LYS142 |
| B | ASN144 |
| B | LYS309 |
| B | VAL313 |
| B | LEU316 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1001 |
| Chain | Residue |
| C | CYS99 |
| C | CYS102 |
| C | CYS110 |
| C | ASP116 |
| site_id | BC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAP C 1002 |
| Chain | Residue |
| A | VAL295 |
| C | ILE192 |
| C | GLY193 |
| C | SER194 |
| C | GLY195 |
| C | SER196 |
| C | GLU197 |
| C | ASN216 |
| C | ARG217 |
| C | HIS218 |
| C | TYR238 |
| C | THR252 |
| C | SER253 |
| C | THR258 |
| C | PHE275 |
| C | PHE277 |
| C | SER304 |
| C | VAL305 |
| C | ASP306 |
| C | LYS349 |
| C | HOH1129 |
| C | HOH1131 |
| C | HOH1147 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGO C 1003 |
| Chain | Residue |
| C | ARG95 |
| C | HIS126 |
| C | ARG130 |
| C | TYR134 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1PE C 1004 |
| Chain | Residue |
| C | LEU140 |
| C | VAL141 |
| C | LYS142 |
| C | ASN144 |
| C | LYS309 |
| C | VAL313 |
| C | LEU316 |
| C | ASP317 |
| D | ASP181 |
| D | ILE185 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1PE C 1005 |
| Chain | Residue |
| B | LYS173 |
| B | ARG174 |
| C | LYS173 |
| C | ILE176 |
| C | GLN178 |
| C | ASN179 |
| C | SER182 |
| C | HOH1155 |
| D | ILE104 |
| D | ARG106 |
| D | GLU166 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1PE D 4001 |
| Chain | Residue |
| A | LYS173 |
| A | SER175 |
| C | ILE104 |
| C | ARG106 |
| D | LYS173 |
| D | ILE176 |
| D | GLN178 |
| D | ASN179 |
| D | SER182 |
| D | HOH4103 |
| D | HOH4132 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 4002 |
| Chain | Residue |
| D | CYS99 |
| D | CYS102 |
| D | CYS110 |
| D | ASP116 |
| site_id | BC9 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAP D 4003 |
| Chain | Residue |
| B | VAL295 |
| D | ASN160 |
| D | ILE192 |
| D | SER194 |
| D | GLY195 |
| D | SER196 |
| D | GLU197 |
| D | ASN216 |
| D | ARG217 |
| D | HIS218 |
| D | TYR238 |
| D | THR252 |
| D | ASP255 |
| D | THR258 |
| D | PHE275 |
| D | PHE277 |
| D | SER304 |
| D | VAL305 |
| D | ASP306 |
| D | HOH4114 |
| D | HOH4158 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO D 4004 |
| Chain | Residue |
| D | ARG95 |
| D | HIS126 |
| D | PHE128 |
| D | ARG130 |
| D | TYR134 |
| D | ASP135 |
| site_id | CC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 1PE D 4005 |
| Chain | Residue |
| C | ASP181 |
| C | ILE185 |
| D | ILE137 |
| D | LEU140 |
| D | VAL141 |
| D | LYS142 |
| D | ASN144 |
| D | LYS309 |
| D | VAL313 |
| D | LEU316 |
| D | ASP317 |
| D | HOH4166 |
