3WHO
X-ray-Crystallographic Structure of an RNase Po1 Exhibiting Anti-tumor Activity
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046589 | molecular_function | ribonuclease T1 activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046589 | molecular_function | ribonuclease T1 activity |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004521 | molecular_function | RNA endonuclease activity |
| C | 0004540 | molecular_function | RNA nuclease activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046589 | molecular_function | ribonuclease T1 activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS36 | |
| B | HIS36 | |
| C | HIS36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU54 | |
| B | GLU54 | |
| C | GLU54 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS87 | |
| B | HIS87 | |
| C | HIS87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:7798182 |
| Chain | Residue | Details |
| A | GLN1 | |
| B | GLN1 | |
| C | GLN1 |
