3WAJ

Crystal structure of the Archaeoglobus fulgidus oligosaccharyltransferase (O29867_ARCFU) complex with Zn and sulfate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004576	molecular_function	oligosaccharyl transferase activity
A	0004579	molecular_function	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
A	0005886	cellular_component	plasma membrane
A	0006486	biological_process	protein glycosylation
A	0016020	cellular_component	membrane
A	0016757	molecular_function	glycosyltransferase activity
A	0018279	biological_process	protein N-linked glycosylation via asparagine
A	0043687	biological_process	post-translational protein modification
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 901

Chain	Residue
A	ASP47
A	ASP161
A	HIS163
A	HOH1001
A	HOH1122
A	HOH1137

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 902

Chain	Residue
A	ARG426
A	HOH1057
A	HOH1067
A	HOH1137
A	HIS81
A	HIS162
A	TRP215

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:24127570

Chain	Residue	Details
A	MET1-VAL16
A	PHE132-ASP133
A	LYS185-ALA199
A	VAL239-ALA241
A	GLY304-GLY312
A	TYR397-SER404
A	TYR453-TYR468

---

site_id	SWS_FT_FI2
Number of Residues	271
Details	TRANSMEM: Helical => ECO:0000269|PubMed:24127570

Chain	Residue	Details
A	LEU17-VAL36
A	GLY102-VAL131
A	LYS134-GLN153
A	HIS163-TRP184
A	TYR200-VAL212
A	GLY216-PHE238
A	ASP242-LEU262
A	GLN280-VAL303
A	ARG313-LEU330
A	LEU374-ALA396
A	PHE405-GLY423
A	ALA428-LEU452
A	PHE469-SER494

---

site_id	SWS_FT_FI3
Number of Residues	508
Details	TOPO_DOM: Extracellular => ECO:0000305|PubMed:24127570

Chain	Residue	Details
A	PHE37-SER101
A	ARG154-HIS162
A	LEU213-TRP215
A	PRO263-PHE279
A	PHE331-THR373
A	GLN424-PHE427
A	TYR495-LEU868

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:24127570, ECO:0000269|PubMed:27997792, ECO:0007744|PDB:3WAK

Chain	Residue	Details
A	HIS163
A	ASP47
A	ASP161

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:24127570

Chain	Residue	Details
A	HIS162
A	ARG426
A	HIS81

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	SITE: Interacts with target acceptor peptide in protein substrate => ECO:0000269|PubMed:27997792

Chain	Residue	Details
A	ASP47
A	GLU360
A	LYS618

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	SITE: Important for catalytic activity => ECO:0000250|UniProtKB:B9KDD4

Chain	Residue	Details
A	ARG154

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