3WAJ
Crystal structure of the Archaeoglobus fulgidus oligosaccharyltransferase (O29867_ARCFU) complex with Zn and sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004576 | molecular_function | oligosaccharyl transferase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006486 | biological_process | obsolete protein glycosylation |
| A | 0009101 | biological_process | glycoprotein biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 901 |
| Chain | Residue |
| A | ASP47 |
| A | ASP161 |
| A | HIS163 |
| A | HOH1001 |
| A | HOH1122 |
| A | HOH1137 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 902 |
| Chain | Residue |
| A | ARG426 |
| A | HOH1057 |
| A | HOH1067 |
| A | HOH1137 |
| A | HIS81 |
| A | HIS162 |
| A | TRP215 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 247 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 466 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Region: {"description":"Interacts with target acceptor peptide in protein substrate","evidences":[{"source":"PubMed","id":"27997792","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Motif: {"description":"DXD motif 1","evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Motif: {"description":"DXD motif 2","evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Motif: {"description":"WWDYG motif","evidences":[{"source":"PubMed","id":"23815857","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 9 |
| Details | Motif: {"description":"DKi motif","evidences":[{"source":"PubMed","id":"23815857","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27997792","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3WAK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24127570","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interacts with target acceptor peptide in protein substrate","evidences":[{"source":"PubMed","id":"27997792","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"B9KDD4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
