3W9F

Crystal structure of the ankyrin repeat domain of chicken TRPV4 in complex with IP3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
B	0005216	molecular_function	monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
C	0005216	molecular_function	monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
D	0005216	molecular_function	monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE I3P A 2001

Chain	Residue
A	ARG235
A	HOH2313
A	HOH2344
A	LYS237
A	ASN282
A	GLN283
A	PRO284
A	HIS285
A	LYS330
A	HOH2273
A	HOH2295

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE I3P B 2001

Chain	Residue
B	ARG235
B	ASN282
B	GLN283
B	PRO284
B	HIS285
B	LYS330
B	HOH2212

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE I3P C 2001

Chain	Residue
C	ARG235
C	LYS237
C	ASN282
C	GLN283
C	PRO284
C	HIS285
C	LYS330

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE I3P D 2001

Chain	Residue
D	ARG235
D	LYS237
D	ASN282
D	PRO284
D	HIS285
D	LYS330

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	116
Details	Repeat: {"description":"ANK 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	116
Details	Repeat: {"description":"ANK 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9HBA0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25256292","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3W9F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	64
Details	Repeat: {"description":"ANK 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---