Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004128 | molecular_function | cytochrome-b5 reductase activity, acting on NAD(P)H |
A | 0005575 | cellular_component | cellular_component |
A | 0005739 | cellular_component | mitochondrion |
A | 0005741 | cellular_component | mitochondrial outer membrane |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0005789 | cellular_component | endoplasmic reticulum membrane |
A | 0006695 | biological_process | cholesterol biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
A | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 32 |
Details | BINDING SITE FOR RESIDUE FAD A 1301 |
Chain | Residue |
A | ARG1063 |
A | THR1088 |
A | HIS1089 |
A | PHE1092 |
A | GLY1095 |
A | GLY1096 |
A | LYS1097 |
A | MET1098 |
A | SER1099 |
A | THR1153 |
A | THR1156 |
A | PRO1064 |
A | PRO1157 |
A | GOL1304 |
A | GOL1305 |
A | HOH2006 |
A | HOH2029 |
A | HOH2060 |
A | HOH2071 |
A | HOH2072 |
A | HOH2187 |
A | HOH2204 |
A | TYR1065 |
A | HOH2226 |
A | HOH2232 |
A | HOH2451 |
A | THR1066 |
A | VAL1080 |
A | ILE1081 |
A | LYS1082 |
A | TYR1084 |
A | PHE1085 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1302 |
Chain | Residue |
A | PRO1038 |
A | GLY1075 |
A | ASP1170 |
A | HOH2058 |
A | HOH2200 |
A | HOH2408 |
A | HOH2411 |
site_id | AC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GOL A 1303 |
Chain | Residue |
A | GLY1151 |
A | GLY1152 |
A | ALA1180 |
A | ASN1181 |
A | GLN1182 |
A | ASP1211 |
A | PHE1223 |
A | PRO1247 |
A | MET1250 |
A | HOH2034 |
A | HOH2164 |
A | HOH2238 |
A | HOH2482 |
A | HOH2524 |
A | HOH2603 |
A | HOH2604 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 1304 |
Chain | Residue |
A | ALA1094 |
A | GLY1095 |
A | LYS1097 |
A | FAD1301 |
A | HOH2088 |
A | HOH2123 |
A | HOH2329 |
A | HOH2436 |
A | HOH2442 |
site_id | AC5 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE GOL A 1305 |
Chain | Residue |
A | GLY1151 |
A | THR1153 |
A | GLY1154 |
A | GLY1246 |
A | PRO1247 |
A | PRO1248 |
A | FAD1301 |
A | HOH2029 |
A | HOH2089 |
A | HOH2451 |
A | HOH2556 |
A | HOH2563 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ARG1063 | |
A | PRO1064 | |
A | TYR1065 | |
A | LYS1097 | |
A | MET1098 | |
A | SER1099 | |
Chain | Residue | Details |
A | VAL1080 | |
A | LYS1082 | |
A | TYR1084 | |
A | THR1156 | |
Chain | Residue | Details |
A | LYS1013 | |
Chain | Residue | Details |
A | TYR1014 | |
Chain | Residue | Details |
A | LYS1021 | |
A | LYS1091 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 862 |
Chain | Residue | Details |
A | HIS1049 | proton shuttle (general acid/base), single electron shuttle |
A | TYR1065 | electrostatic stabiliser |
A | THR1066 | proton shuttle (general acid/base), single electron shuttle |
A | CYS1245 | alter redox potential |