3W3S

Crystal structure of A. aeolicus tRNASec in complex with M. kandleri SerRS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004828	molecular_function	serine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006434	biological_process	seryl-tRNA aminoacylation
A	0008270	molecular_function	zinc ion binding
A	0016260	biological_process	selenocysteine biosynthetic process
A	0016874	molecular_function	ligase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 2001

Chain	Residue
A	CYS319
A	GLU368
A	CYS478
A	SSA2002

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SSA A 2002

Chain	Residue
A	ARG366
A	GLU368
A	PHE409
A	SER449
A	VAL450
A	GLY451
A	SER452
A	ASN454
A	CYS478
A	GLY482
A	ARG485
A	ZN2001
A	ALA317
A	ARG349
A	GLU351
A	VAL361
A	PHE364

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 2003

Chain	Residue
A	PHE364
A	ARG485

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 2004

Chain	Residue
A	TYR410

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 2006

Chain	Residue
B	U47

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 2007

Chain	Residue
A	HIS74

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PT A 2009

Chain	Residue
A	ARG260
A	HIS263
A	LEU416

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PT A 2010

Chain	Residue
A	GLU105
A	GLU131
A	ARG136

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site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 2012

Chain	Residue
A	GLY194

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PT A 2013

Chain	Residue
A	ARG166
A	SER167
A	ARG414

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 2015

Chain	Residue
A	GLU144

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 2017

Chain	Residue
A	GLU511
A	LYS512

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2018

Chain	Residue
A	ARG40
A	ARG83

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 2019

Chain	Residue
A	ARG40
A	GLY41
B	A47
B	G47

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 2020

Chain	Residue
A	MSE1
A	PHE110
A	ASP111
A	ARG112
A	GLU164

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site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2021

Chain	Residue
A	ASN296
A	GLU297

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2022

Chain	Residue
A	ARG308
A	ASP309

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site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2023

Chain	Residue
A	ARG212
A	ARG308

---

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 B 101

Chain	Residue
B	G47

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 102

Chain	Residue
B	C47
B	C47
B	C47

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01278","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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