Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004325 | molecular_function | ferrochelatase activity |
| A | 0006783 | biological_process | heme biosynthetic process |
| B | 0004325 | molecular_function | ferrochelatase activity |
| B | 0006783 | biological_process | heme biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FES A 1501 |
| Chain | Residue |
| A | CYS196 |
| A | SER402 |
| A | CYS403 |
| A | CYS406 |
| A | CYS411 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CHD A 1502 |
| Chain | Residue |
| A | HIS263 |
| A | VAL269 |
| A | TRP310 |
| A | CHD1503 |
| A | HOH1620 |
| A | HOH1640 |
| A | HOH1643 |
| A | HOH1653 |
| A | HOH1739 |
| A | HOH1784 |
| A | MET76 |
| A | LEU92 |
| A | LEU98 |
| A | SER197 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CHD A 1503 |
| Chain | Residue |
| A | ARG114 |
| A | LEU115 |
| A | MET308 |
| A | TRP310 |
| A | CHD1502 |
| A | CHD1504 |
| A | HOH1657 |
| A | HOH1711 |
| A | HOH1759 |
| A | HOH1791 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CHD A 1504 |
| Chain | Residue |
| A | THR100 |
| A | LEU101 |
| A | PRO102 |
| A | LEU107 |
| A | CHD1503 |
| B | LYS106 |
| B | PHE110 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SAL A 1505 |
| Chain | Residue |
| A | PRO277 |
| A | GLN278 |
| A | SER281 |
| B | PRO277 |
| B | GLN278 |
| B | SER281 |
| B | TRP301 |
| B | LEU311 |
| B | HOH605 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1506 |
| Chain | Residue |
| A | ASP97 |
| A | CYS196 |
| A | SER201 |
| A | ASN204 |
| A | ASN408 |
| A | CYS411 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CHD A 1507 |
| Chain | Residue |
| A | GLU80 |
| A | ILE126 |
| A | GLY127 |
| A | GLY129 |
| A | THR400 |
| A | ARG412 |
| A | LYS415 |
| A | HOH1696 |
| A | HOH1743 |
| B | ARG327 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FES B 501 |
| Chain | Residue |
| B | CYS196 |
| B | ARG272 |
| B | CYS403 |
| B | CYS406 |
| B | CYS411 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CHD B 502 |
| Chain | Residue |
| B | ARG114 |
| B | TRP310 |
| B | CHD503 |
| B | HOH800 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CHD B 503 |
| Chain | Residue |
| A | PHE110 |
| B | THR100 |
| B | PRO102 |
| B | LEU107 |
| B | CHD502 |
| site_id | BC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CHD B 504 |
| Chain | Residue |
| B | LEU92 |
| B | PHE93 |
| B | LEU98 |
| B | SER197 |
| B | HIS263 |
| B | TRP310 |
| B | HOH638 |
| B | HOH640 |
| B | HOH660 |
| B | HOH665 |
| B | HOH670 |
| B | HOH701 |
| B | HOH754 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 505 |
| Chain | Residue |
| B | ASP97 |
| B | CYS196 |
| B | GLY200 |
| B | SER201 |
| B | ASN204 |
| B | ASN408 |
| B | CYS411 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CHD B 506 |
| Chain | Residue |
| B | GLY127 |
| B | GLY129 |
| B | LEU345 |
| B | THR400 |
| B | LYS415 |
| B | HOH709 |
| B | HOH813 |
| A | GLY326 |
| A | ARG327 |
| B | GLU80 |
| B | ILE126 |
Functional Information from PROSITE/UniProt
| site_id | PS00534 |
| Number of Residues | 19 |
| Details | FERROCHELATASE Ferrochelatase signature. ILfSaHSLPmsvv.NrGDp...Y |
| Chain | Residue | Details |
| A | ILE258-TYR276 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | HIS230 | |
| A | ASP383 | |
| B | HIS230 | |
| B | ASP383 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS196 | |
| A | CYS403 | |
| A | CYS406 | |
| A | CYS411 | |
| B | CYS196 | |
| B | CYS403 | |
| B | CYS406 | |
| B | CYS411 | |
| Chain | Residue | Details |
| A | LYS138 | |
| B | LYS138 | |
| Chain | Residue | Details |
| A | LYS415 | |
| B | LYS415 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 578 |
| Chain | Residue | Details |
| A | MET76 | |
| A | LEU92 | |
| A | LEU98 | |
| A | ARG164 | |
| A | TYR165 | |
| A | HIS263 | metal ligand, proton acceptor |
| A | ASP340 | |
| A | GLU343 | metal ligand, proton acceptor |
| A | GLU347 | |
| site_id | MCSA2 |
| Number of Residues | 9 |
| Details | M-CSA 578 |
| Chain | Residue | Details |
| B | MET76 | |
| B | LEU92 | |
| B | LEU98 | |
| B | ARG164 | |
| B | TYR165 | |
| B | HIS263 | metal ligand, proton acceptor |
| B | ASP340 | |
| B | GLU343 | metal ligand, proton acceptor |
| B | GLU347 | |
