3W15
Structure of peroxisomal targeting signal 2 (PTS2) of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase in complex with Pex7p and Pex21p
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005053 | molecular_function | peroxisome matrix targeting signal-2 binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005778 | cellular_component | peroxisomal membrane |
| A | 0005782 | cellular_component | peroxisomal matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0015031 | biological_process | protein transport |
| A | 0016558 | biological_process | protein import into peroxisome matrix |
| A | 0016560 | biological_process | protein import into peroxisome matrix, docking |
| A | 0062137 | cellular_component | cargo receptor complex |
| A | 0072663 | biological_process | establishment of protein localization to peroxisome |
| C | 0005515 | molecular_function | protein binding |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0015768 | biological_process | maltose transport |
| C | 0016020 | cellular_component | membrane |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0034219 | biological_process | carbohydrate transmembrane transport |
| C | 0034289 | biological_process | detection of maltose stimulus |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0042956 | biological_process | maltodextrin transmembrane transport |
| C | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| C | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| C | 0055085 | biological_process | transmembrane transport |
| C | 0060326 | biological_process | cell chemotaxis |
| C | 0071702 | biological_process | organic substance transport |
| C | 1901982 | molecular_function | maltose binding |
| C | 1990060 | cellular_component | maltose transport complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 A 401 |
| Chain | Residue |
| A | GLU149 |
| A | TYR198 |
| A | LEU216 |
| C | ASP58 |
| C | LYS63 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 402 |
| Chain | Residue |
| A | THR90 |
| A | HOH617 |
| A | HOH620 |
| A | ARG23 |
| A | ILE42 |
| A | VAL54 |
| A | ASN55 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | ASP65 |
| A | LEU66 |
| A | CYS110 |
| A | ASN111 |
| A | HOH506 |
| A | HOH508 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NO3 B 301 |
| Chain | Residue |
| B | HIS283 |
| B | LYS284 |
| B | ILE286 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 C 401 |
| Chain | Residue |
| C | ASN29 |
| C | LYS32 |
| C | TRP79 |
| C | ALA80 |
| C | LEU279 |
| C | HOH512 |
| C | HOH728 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 C 402 |
| Chain | Residue |
| C | TYR259 |
| C | GLY260 |
| C | VAL261 |
| C | PRO332 |
| C | ARG333 |
| C | HOH681 |
| C | HOH771 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 C 403 |
| Chain | Residue |
| C | TYR184 |
| C | ALA185 |
| C | PHE186 |
| C | PHE275 |
| C | GLU345 |
| C | PRO348 |
| C | HOH601 |
| C | HOH688 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 C 404 |
| Chain | Residue |
| C | LYS157 |
| C | LYS219 |
| C | HIS220 |
| C | MET221 |
| C | ASN222 |
| C | HOH591 |
| C | HOH708 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 C 405 |
| Chain | Residue |
| C | PRO246 |
| C | TRP249 |
| C | PRO315 |
| C | GLY317 |
| C | HOH648 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 C 406 |
| Chain | Residue |
| C | ASN29 |
| C | GLY30 |
| C | ASP31 |
| C | HOH775 |
| C | HOH865 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 407 |
| Chain | Residue |
| C | HOH607 |
| C | HOH608 |
| C | HOH609 |
| C | HOH610 |
| C | HOH611 |
| C | HOH612 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 408 |
| Chain | Residue |
| C | ASP72 |
| C | HOH504 |
| C | HOH505 |
| C | HOH506 |
| C | HOH507 |
| C | HOH508 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 409 |
| Chain | Residue |
| C | HOH671 |
| C | HOH672 |
| C | HOH673 |
| C | HOH674 |
| C | HOH675 |
| C | HOH744 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 410 |
| Chain | Residue |
| C | ASP226 |
| C | HOH633 |
| C | HOH634 |
| C | HOH635 |
| C | HOH636 |
| C | HOH637 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 411 |
| Chain | Residue |
| C | HOH798 |
| C | HOH865 |
| C | HOH887 |
| C | HOH888 |
| C | HOH889 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGgvDnAIRIWDI |
| Chain | Residue | Details |
| A | VAL236-ILE250 | |
| A | VAL359-GLY373 |
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| C | PRO124-ASN141 |
Catalytic Information from CSA
