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3VZV

Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
B0005634cellular_componentnucleus
B0043066biological_processnegative regulation of apoptotic process
B0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE VZV A 200
ChainResidue
ALEU54
AGLY58
AMET62
ATYR67
AGLN72
AVAL93
AHIS96
ATYR100
BTYR104

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE VZV B 201
ChainResidue
ATHR26
ATYR100
ATYR104
BLEU54
BMET62
BGLN72
BVAL93
BHIS96
BILE99

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues166
DetailsDomain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

248335

PDB entries from 2026-01-28

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