3VZ0

Structural insights into cofactor and substrate selection by Gox0499

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
A	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
B	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
C	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
D	0004777	molecular_function	succinate-semialdehyde dehydrogenase (NAD+) activity
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 2PE A 501

Chain	Residue
A	GLU84
A	PHE427
A	VAL88
A	PHE134
A	TYR137
A	TRP251
A	TRP254
A	THR265
A	ALA420
A	ALA421

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 2PE B 501

Chain	Residue
B	GLU84
B	PHE134
B	TYR137
B	TRP251
B	TRP254
B	THR265
B	ALA420
B	ALA421
B	PHE427

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 2PE C 501

Chain	Residue
C	PHE134
C	TYR137
C	TRP251
C	TRP254
C	THR265
C	ALA420
C	ALA421
C	PHE427

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site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 2PE D 501

Chain	Residue
D	VAL88
D	PHE134
D	TYR137
D	TRP251
D	THR265
D	ALA420
D	ALA421
D	PHE427

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Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FaNNGQVCTAAK

Chain	Residue	Details
A	PHE257-LYS268

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