3VXG

Crystal structure of conjugated polyketone reductase C2 from Candida Parapsilosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005575	cellular_component	cellular_component
A	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
A	0016491	molecular_function	oxidoreductase activity
A	0016652	molecular_function	oxidoreductase activity, acting on NAD(P)H as acceptor
A	0036441	molecular_function	2-dehydropantolactone reductase activity
A	0042180	biological_process	ketone metabolic process
A	0047011	molecular_function	2-dehydropantolactone reductase (A-specific) activity

Functional Information from PROSITE/UniProt

site_id	PS00422
Number of Residues	10
Details	GRANINS_1 Granins signature 1. ESLNLFDfEL

Chain	Residue	Details
A	GLU270-LEU279

---

site_id	PS00798
Number of Residues	18
Details	ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GFRHIDTAeayntQkeVG

Chain	Residue	Details
A	GLY53-GLY70

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"23828603","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23828603","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4H8N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Lowers pKa of active site Tyr","evidences":[{"source":"PubMed","id":"23828603","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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