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4H8N

Crystal structure of conjugated polyketone reductase C2 from candida parapsilosis complexed with NADPH

Summary for 4H8N
Entry DOI10.2210/pdb4h8n/pdb
Related3VXG
DescriptorConjugated polyketone reductase C2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsoxidoreductase, tim barrel, d-pantoyl lactone
Biological sourceCandida parapsilosis (Yeast)
Total number of polymer chains2
Total formula weight71443.99
Authors
Qin, H.-M.,Yamamura, A.,Miyakawa, T.,Maruoka, S.,Ohtsuka, J.,Nagata, K.,Kataoka, M.,Shimizu, S.,Tanokura, M. (deposition date: 2012-09-23, release date: 2013-08-07, Last modification date: 2023-11-08)
Primary citationQin, H.-M.,Yamamura, A.,Miyakawa, T.,Kataoka, M.,Nagai, T.,Kitamura, N.,Urano, N.,Maruoka, S.,Ohtsuka, J.,Nagata, K.,Shimizu, S.,Tanokura, M.
Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding
Appl.Microbiol.Biotechnol., 98:243-249, 2014
Cited by
PubMed: 23828603
DOI: 10.1007/s00253-013-5073-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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