3VTW

Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
A	0000421	cellular_component	autophagosome membrane
A	0000422	biological_process	autophagy of mitochondrion
A	0000423	biological_process	mitophagy
A	0005515	molecular_function	protein binding
A	0005543	molecular_function	phospholipid binding
A	0005739	cellular_component	mitochondrion
A	0005776	cellular_component	autophagosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0005930	cellular_component	axoneme
A	0006914	biological_process	autophagy
A	0006995	biological_process	cellular response to nitrogen starvation
A	0008017	molecular_function	microtubule binding
A	0008429	molecular_function	phosphatidylethanolamine binding
A	0009267	biological_process	cellular response to starvation
A	0012505	cellular_component	endomembrane system
A	0016020	cellular_component	membrane
A	0016236	biological_process	macroautophagy
A	0031090	cellular_component	organelle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0031966	cellular_component	mitochondrial membrane
A	0097001	molecular_function	ceramide binding
A	0097352	biological_process	autophagosome maturation
B	0000045	biological_process	autophagosome assembly
B	0000421	cellular_component	autophagosome membrane
B	0000422	biological_process	autophagy of mitochondrion
B	0000423	biological_process	mitophagy
B	0005515	molecular_function	protein binding
B	0005543	molecular_function	phospholipid binding
B	0005739	cellular_component	mitochondrion
B	0005776	cellular_component	autophagosome
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0005930	cellular_component	axoneme
B	0006914	biological_process	autophagy
B	0006995	biological_process	cellular response to nitrogen starvation
B	0008017	molecular_function	microtubule binding
B	0008429	molecular_function	phosphatidylethanolamine binding
B	0009267	biological_process	cellular response to starvation
B	0012505	cellular_component	endomembrane system
B	0016020	cellular_component	membrane
B	0016236	biological_process	macroautophagy
B	0031090	cellular_component	organelle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0031966	cellular_component	mitochondrial membrane
B	0097001	molecular_function	ceramide binding
B	0097352	biological_process	autophagosome maturation
C	0000045	biological_process	autophagosome assembly
C	0000421	cellular_component	autophagosome membrane
C	0000422	biological_process	autophagy of mitochondrion
C	0000423	biological_process	mitophagy
C	0005515	molecular_function	protein binding
C	0005543	molecular_function	phospholipid binding
C	0005739	cellular_component	mitochondrion
C	0005776	cellular_component	autophagosome
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0005930	cellular_component	axoneme
C	0006914	biological_process	autophagy
C	0006995	biological_process	cellular response to nitrogen starvation
C	0008017	molecular_function	microtubule binding
C	0008429	molecular_function	phosphatidylethanolamine binding
C	0009267	biological_process	cellular response to starvation
C	0012505	cellular_component	endomembrane system
C	0016020	cellular_component	membrane
C	0016236	biological_process	macroautophagy
C	0031090	cellular_component	organelle membrane
C	0031410	cellular_component	cytoplasmic vesicle
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0031966	cellular_component	mitochondrial membrane
C	0097001	molecular_function	ceramide binding
C	0097352	biological_process	autophagosome maturation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	LYS23
A	PHE28
A	ARG31
B	ARG84

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 201

Chain	Residue
B	VAL12
B	LYS64
B	ARG85
B	HOH327

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 202

Chain	Residue
B	ARG39
A	LYS54

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 201

Chain	Residue
C	PRO17
C	SER18

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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