3VQ2

Crystal structure of mouse TLR4/MD-2/LPS complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0001530	molecular_function	lipopolysaccharide binding
C	0035662	molecular_function	Toll-like receptor 4 binding
C	0045087	biological_process	innate immune response
D	0001530	molecular_function	lipopolysaccharide binding
D	0035662	molecular_function	Toll-like receptor 4 binding
D	0045087	biological_process	innate immune response

Functional Information from PROSITE/UniProt

site_id	PS00159
Number of Residues	10
Details	ALDOLASE_KDPG_KHG_1 KDPG and KHG aldolases active site. GIklhELTLR

Chain	Residue	Details
A	GLY224-ARG233

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64

Chain	Residue	Details
C	ASN26
B	ASN34
B	ASN75
B	ASN172
B	ASN204
B	ASN237
B	ASN307
B	ASN492
B	ASN524
B	ASN572
D	ASN26
A	ASN172
A	ASN204
A	ASN237
A	ASN307
A	ASN492
A	ASN524
A	ASN572

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912

Chain	Residue	Details
C	ASN114
B	ASN622
C	ASN150
D	ASN114
D	ASN150
A	ASN622
B	ASN495
B	ASN575
B	ASN613
B	ASN621

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