3VOM
Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| A | 0004760 | molecular_function | L-serine-pyruvate transaminase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006563 | biological_process | L-serine metabolic process |
| A | 0006564 | biological_process | L-serine biosynthetic process |
| A | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| B | 0004760 | molecular_function | L-serine-pyruvate transaminase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005777 | cellular_component | peroxisome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006563 | biological_process | L-serine metabolic process |
| B | 0006564 | biological_process | L-serine biosynthetic process |
| B | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0008615 | biological_process | pyridoxine biosynthetic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP A 401 |
| Chain | Residue |
| A | ALA84 |
| A | GLN199 |
| A | LYS200 |
| A | HOH517 |
| B | ASN251 |
| B | THR252 |
| B | GOL403 |
| B | HOH563 |
| A | THR85 |
| A | TRP88 |
| A | PHE108 |
| A | ASN152 |
| A | THR154 |
| A | ASP176 |
| A | THR178 |
| A | ALA197 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | HIS49 |
| A | ARG50 |
| A | HOH649 |
| A | HOH723 |
| A | HOH836 |
| A | HOH845 |
| B | PHE108 |
| B | TYR341 |
| B | PLP401 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | SER134 |
| A | THR303 |
| A | HOH569 |
| A | HOH741 |
| B | LEU245 |
| B | HOH582 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP B 401 |
| Chain | Residue |
| A | ASN251 |
| A | THR252 |
| A | SO4402 |
| B | ALA84 |
| B | THR85 |
| B | TRP88 |
| B | PHE108 |
| B | ASN152 |
| B | THR154 |
| B | ASP176 |
| B | THR178 |
| B | ALA197 |
| B | GLN199 |
| B | LYS200 |
| B | HOH518 |
| B | HOH530 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| B | ARG62 |
| B | SER63 |
| B | GLU76 |
| B | VAL77 |
| B | HOH631 |
| B | HOH822 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 403 |
| Chain | Residue |
| A | TYR341 |
| A | ARG342 |
| A | PLP401 |
| B | HIS49 |
| B | ARG50 |
| B | HOH563 |
| B | HOH691 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22525753","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
