Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE 0JA A 2001 |
Chain | Residue |
A | VAL848 |
A | VAL916 |
A | GLU917 |
A | PHE918 |
A | CYS919 |
A | LYS920 |
A | GLY922 |
A | LEU1019 |
A | LEU1035 |
A | ILE1044 |
A | CYS1045 |
A | ALA866 |
A | ASP1046 |
A | PHE1047 |
A | EDO2002 |
A | HOH3072 |
A | HOH3221 |
A | LYS868 |
A | GLU885 |
A | LEU889 |
A | ILE892 |
A | VAL898 |
A | VAL899 |
A | VAL914 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 2002 |
Chain | Residue |
A | GLY922 |
A | ASN923 |
A | PHE1047 |
A | 0JA2001 |
A | HOH3120 |
A | HOH3136 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 2003 |
Chain | Residue |
A | ALA1020 |
A | GLN1085 |
A | THR1152 |
A | PHE1153 |
A | SER1154 |
A | HOH3092 |
A | HOH3121 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 2004 |
Chain | Residue |
A | TRP1096 |
A | SER1100 |
A | PRO1128 |
A | ASP1129 |
A | HOH3009 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 29 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGAFGQVIeAdafgidktatcrt.....VAVK |
Chain | Residue | Details |
A | LEU840-LYS868 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNILL |
Chain | Residue | Details |
A | CYS1024-LEU1036 | |
site_id | PS00240 |
Number of Residues | 14 |
Details | RECEPTOR_TYR_KIN_III Receptor tyrosine kinase class III signature. GhHlNVVNLLGACT |
Chain | Residue | Details |
A | GLY893-THR906 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | PHE1078 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000305 |
Chain | Residue | Details |
A | LEU840 | |
A | LYS868 | |
Chain | Residue | Details |
A | THR1001 | |
Chain | Residue | Details |
A | ARG1032 | |
A | ILE1034 | |
Chain | Residue | Details |
A | ASP1046 | |
Chain | Residue | Details |
A | SER1104 | |
Chain | Residue | Details |
A | VAL1109 | |