Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

3VI3

Crystal structure of alpha5beta1 integrin headpiece (ligand-free form)

Functional Information from GO Data
ChainGOidnamespacecontents
A0007155biological_processcell adhesion
A0008305cellular_componentintegrin complex
C0007155biological_processcell adhesion
C0008305cellular_componentintegrin complex
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR197-HIS203
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues130
DetailsRepeat: {"description":"FG-GAP 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues120
DetailsRepeat: {"description":"FG-GAP 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues106
DetailsRepeat: {"description":"FG-GAP 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues104
DetailsRepeat: {"description":"FG-GAP 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues130
DetailsRepeat: {"description":"FG-GAP 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues118
DetailsRepeat: {"description":"FG-GAP 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues126
DetailsRepeat: {"description":"FG-GAP 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues40
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues8
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues9
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues476
DetailsDomain: {"description":"VWFA","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues64
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues12
DetailsRegion: {"description":"CX3CL1-binding","evidences":[{"source":"PubMed","id":"23125415","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues38
DetailsRegion: {"description":"CX3CL1-binding","evidences":[{"source":"PubMed","id":"24789099","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues164
DetailsRegion: {"description":"Interaction with TMEM182","evidences":[{"source":"UniProtKB","id":"P07228","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues20
DetailsCompositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI21
Number of Residues4
DetailsBinding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI22
Number of Residues2
DetailsBinding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI23
Number of Residues6
DetailsBinding site: {"description":"in ADMIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI24
Number of Residues2
DetailsBinding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI25
Number of Residues6
DetailsBinding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI26
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI27
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI28
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI29
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

238582

PDB entries from 2025-07-09

PDB statisticsPDBj update infoContact PDBjnumon