3VGJ
Crystal of Plasmodium falciparum tyrosyl-tRNA synthetase (PfTyrRS)in complex with adenylate analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004831 | molecular_function | tyrosine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006437 | biological_process | tyrosyl-tRNA aminoacylation |
| A | 0044164 | cellular_component | host cell cytosol |
| A | 0044650 | biological_process | adhesion of symbiont to host cell |
| A | 0046789 | molecular_function | host cell surface receptor binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004831 | molecular_function | tyrosine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006437 | biological_process | tyrosyl-tRNA aminoacylation |
| B | 0044164 | cellular_component | host cell cytosol |
| B | 0044650 | biological_process | adhesion of symbiont to host cell |
| B | 0046789 | molecular_function | host cell surface receptor binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TYR A 401 |
| Chain | Residue |
| A | TYR60 |
| A | GLN210 |
| A | AMP402 |
| A | GLY62 |
| A | GLU64 |
| A | TRP94 |
| A | ALA96 |
| A | ILE172 |
| A | TYR188 |
| A | GLN192 |
| A | ASP195 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE AMP A 402 |
| Chain | Residue |
| A | ASP61 |
| A | GLY62 |
| A | PHE63 |
| A | GLU64 |
| A | HIS70 |
| A | ALA72 |
| A | GLN73 |
| A | LEU206 |
| A | GLY207 |
| A | ASP209 |
| A | GLN210 |
| A | HIS235 |
| A | GLY236 |
| A | MET237 |
| A | LEU238 |
| A | LYS247 |
| A | MET248 |
| A | TYR401 |
| A | HOH532 |
| A | HOH660 |
| A | HOH661 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TYR B 401 |
| Chain | Residue |
| B | TYR60 |
| B | GLY62 |
| B | GLU64 |
| B | TRP94 |
| B | ALA96 |
| B | ILE172 |
| B | TYR188 |
| B | GLN192 |
| B | ASP195 |
| B | GLN210 |
| B | AMP402 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE AMP B 402 |
| Chain | Residue |
| B | ASP61 |
| B | GLY62 |
| B | PHE63 |
| B | GLU64 |
| B | HIS70 |
| B | ALA72 |
| B | GLN73 |
| B | LEU206 |
| B | GLY207 |
| B | ASP209 |
| B | HIS235 |
| B | GLY236 |
| B | MET237 |
| B | LEU238 |
| B | LYS247 |
| B | MET248 |
| B | TYR401 |
| B | HOH504 |
| B | HOH521 |
| B | HOH670 |
