3VBG
Structure of hDM2 with Dimer Inducing Indolyl Hydantoin RO-2443
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
| D | 0005634 | cellular_component | nucleus |
| D | 0043066 | biological_process | negative regulation of apoptotic process |
| D | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 03M A 1 |
| Chain | Residue |
| A | MET62 |
| B | VAL93 |
| B | ILE99 |
| A | ARG65 |
| A | TYR67 |
| A | GLN72 |
| A | VAL93 |
| B | 03M1 |
| B | LEU54 |
| B | LEU57 |
| B | GLY58 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 03M B 1 |
| Chain | Residue |
| A | 03M1 |
| A | LEU54 |
| A | LEU57 |
| A | GLY58 |
| A | VAL93 |
| A | ILE99 |
| B | GLY58 |
| B | ILE61 |
| B | MET62 |
| B | TYR67 |
| B | GLN72 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 03M C 1 |
| Chain | Residue |
| C | TYR67 |
| C | GLU69 |
| C | GLN72 |
| D | 03M1 |
| D | LEU54 |
| D | LEU57 |
| D | GLY58 |
| D | ILE61 |
| D | VAL93 |
| D | ILE99 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 03M D 1 |
| Chain | Residue |
| C | 03M1 |
| C | LEU54 |
| C | LEU57 |
| C | VAL93 |
| C | ILE99 |
| D | ILE61 |
| D | MET62 |
| D | ARG65 |
| D | TYR67 |
| D | GLN72 |
