3V8I
Crystal Structure of a Drosophila melanogaster Dopamine N-Acetyltransferase
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE A 301 |
| Chain | Residue |
| A | LEU146 |
| A | HOH528 |
| B | ASP132 |
| A | VAL148 |
| A | ARG153 |
| A | GLY154 |
| A | ALA158 |
| A | SER186 |
| A | HOH404 |
| A | HOH422 |
| A | HOH438 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE EPE B 301 |
| Chain | Residue |
| A | ASP132 |
| A | HOH403 |
| B | VAL148 |
| B | ARG153 |
| B | GLY154 |
| B | ILE157 |
| B | ALA158 |
| B | TYR185 |
| B | HOH401 |
| B | HOH402 |
| B | HOH417 |
| B | HOH576 |
| B | HOH676 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 146 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22716280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3TE4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Site: {"description":"Has a role in the catalytic activity","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Might be involved in substrate binding","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Regulates binding affinity for coenzyme A (CoASH)","evidences":[{"source":"PubMed","id":"25406072","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Acetyl-CoA","evidences":[{"source":"PubMed","id":"22716280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3TE4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
