3V1H

Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE INS A 401

Chain	Residue
A	HIS30
A	HOH693
A	ARG67
A	LYS113
A	ARG166
A	TRP185
A	ASP206
A	TYR208
A	HOH502
A	HOH624

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 402

Chain	Residue
A	LYS113
A	ARG166
A	TRP185
A	HOH505

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 403

Chain	Residue
A	LEU37
A	LYS38
A	ASP39
A	LYS42
A	HIS86
A	TYR290

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00270

Chain	Residue	Details
A	HIS30

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU00270

Chain	Residue	Details
A	HIS80

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