3UTN

Crystal structure of Tum1 protein from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0002098	biological_process	tRNA wobble uridine modification
X	0002143	biological_process	tRNA wobble position uridine thiolation
X	0004792	molecular_function	thiosulfate-cyanide sulfurtransferase activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0016740	molecular_function	transferase activity
X	0016783	molecular_function	sulfurtransferase activity
X	0016784	molecular_function	3-mercaptopyruvate sulfurtransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DMS X 401

Chain	Residue
X	PRO2
X	ASP5
X	PRO117
X	LYS118
X	VAL119
X	TYR120
X	HOH558

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DMS X 402

Chain	Residue
X	GLY231
X	GLU232
X	GLU297
X	TRP298
X	PRO209
X	ALA230

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS X 403

Chain	Residue
X	PRO2
X	PHE4
X	LYS173
X	LEU274
X	HOH758

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DMS X 404

Chain	Residue
X	PRO251
X	SER252
X	LYS253
X	PRO254
X	PRO278
X	ASN279

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DMS X 405

Chain	Residue
X	SER156
X	PHE157
X	GLN158
X	ASP159

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DMS X 406

Chain	Residue
X	LYS14
X	LYS41
X	HOH793

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DMS X 407

Chain	Residue
X	ILE7
X	TYR120

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DMS X 408

Chain	Residue
X	LEU292
X	LYS293
X	GLY295

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS X 409

Chain	Residue
X	LYS20
X	ALA60
X	ALA81
X	ASN84
X	LEU85

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 X 410

Chain	Residue
X	ALA178
X	GLY210
X	THR211
X	GLN212
X	HOH788

---

Functional Information from PROSITE/UniProt

site_id	PS00683
Number of Residues	11
Details	RHODANESE_2 Rhodanese C-terminal signature. VrlYDGSWtEW

Chain	Residue	Details
X	VAL280-TRP290

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	117
Details	Domain: {"description":"Rhodanese 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00173","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	122
Details	Domain: {"description":"Rhodanese 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00173","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	31
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00173","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22587783","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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