Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE ZPX A 394 |
Chain | Residue |
A | GLY11 |
A | GLN73 |
A | PHE108 |
A | TRP115 |
A | ASP228 |
A | SER229 |
A | GLY230 |
A | THR231 |
A | THR232 |
A | ASN233 |
A | ARG235 |
A | GLN12 |
A | ARG307 |
A | SER325 |
A | ALA335 |
A | HOH633 |
A | GLY13 |
A | TYR14 |
A | LEU30 |
A | ASP32 |
A | GLY34 |
A | TYR71 |
A | THR72 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 395 |
Chain | Residue |
A | THR72 |
A | ARG235 |
A | SER327 |
A | SER328 |
A | THR329 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 396 |
Chain | Residue |
A | TYR51 |
A | GLN53 |
A | GLN55 |
A | LYS218 |
A | HOH630 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 397 |
Chain | Residue |
A | PRO70 |
A | ARG351 |
A | HOH548 |
A | HOH671 |
A | HOH697 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE URE A 398 |
Chain | Residue |
A | ARG61 |
A | ASP62 |
A | HOH480 |
A | HOH621 |
site_id | AC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL A 399 |
site_id | AC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE URE A 400 |
Chain | Residue |
A | ASP62 |
A | LEU213 |
A | MET215 |
A | HOH543 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP32 | |
A | ASP228 | |
Chain | Residue | Details |
A | LYS65 | |
A | LYS214 | |
A | LYS218 | |
A | LYS224 | |
A | LYS238 | |
A | LYS239 | |
A | LYS246 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN92 | |
A | ASN111 | |
A | ASN162 | |
A | ASN293 | |