Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3UKH

Crystal structure of udp-galactopyranose mutase from Aspergillus fumigatus in complex with UDPGALP (non-reduced)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization
E	0000166	molecular_function	nucleotide binding
E	0008767	molecular_function	UDP-galactopyranose mutase activity
E	0016853	molecular_function	isomerase activity
E	0071555	biological_process	cell wall organization
F	0000166	molecular_function	nucleotide binding
F	0008767	molecular_function	UDP-galactopyranose mutase activity
F	0016853	molecular_function	isomerase activity
F	0071555	biological_process	cell wall organization
G	0000166	molecular_function	nucleotide binding
G	0008767	molecular_function	UDP-galactopyranose mutase activity
G	0016853	molecular_function	isomerase activity
G	0071555	biological_process	cell wall organization
H	0000166	molecular_function	nucleotide binding
H	0008767	molecular_function	UDP-galactopyranose mutase activity
H	0016853	molecular_function	isomerase activity
H	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FAD A 600

Chain	Residue
A	GLY14
A	GLY61
A	HIS63
A	GLY240
A	VAL242
A	MET269
A	THR295
A	ARG327
A	GLU373
A	GLY418
A	TYR419
A	GLY16
A	GLY446
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	GDU521
A	HOH525
A	HOH531
A	HOH565
A	PRO17
A	HOH579
A	HOH685
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	ALA47

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GDU A 521

Chain	Residue
A	ILE65
A	TYR104
A	PHE158
A	MET159
A	TYR162
A	ASN163
A	ARG182
A	VAL183
A	TRP315
A	TYR317
A	ARG327
A	TYR419
A	TYR453
A	ASN457
A	CL522
A	FAD600
A	HOH1239
A	HOH1240

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 522

Chain	Residue
A	TYR104
A	PRO105
A	PHE106
A	GLN107
A	GDU521
A	HOH944

site_id	AC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD B 600

Chain	Residue
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	GLY61
B	HIS63
B	GLY240
B	VAL242
B	MET269
B	THR295
B	ARG327
B	GLU373
B	GLY418
B	TYR419
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	GDU521
B	HOH528
B	HOH529
B	HOH540

site_id	AC5
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GDU B 521

Chain	Residue
B	FAD600
B	HOH602
B	HOH645
B	HOH1158
B	HOH1234
B	ILE65
B	VAL95
B	TYR104
B	PHE158
B	MET159
B	TYR162
B	ASN163
B	VAL166
B	ARG182
B	VAL183
B	TYR317
B	ARG327
B	TYR419
B	TYR453
B	ASN457

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1

Chain	Residue
B	ARG160
B	PRO170
B	THR171

site_id	AC7
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FDA C 600

Chain	Residue
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	VAL60
C	GLY61
C	GLY62
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	MET269
C	ARG327
C	GLU373
C	GLY418
C	TYR419
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	GDU521
C	HOH522
C	HOH525
C	HOH580

site_id	AC8
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GDU C 521

Chain	Residue
C	ILE65
C	VAL95
C	TYR104
C	PHE158
C	MET159
C	TYR162
C	ASN163
C	TRP167
C	ARG182
C	VAL183
C	TYR317
C	ARG327
C	TYR419
C	TYR453
C	ASN457
C	FDA600
C	HOH995
C	HOH1160
C	HOH1242

site_id	AC9
Number of Residues	27
Details	BINDING SITE FOR RESIDUE FAD D 600

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	GLY61
D	GLY62
D	HIS63
D	GLY240
D	VAL242
D	MET269
D	THR295
D	ARG327
D	GLY418
D	TYR419
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	GDU521
D	HOH522
D	HOH525

site_id	BC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDU D 521

Chain	Residue
D	ILE65
D	VAL95
D	TYR104
D	PHE106
D	PHE158
D	MET159
D	TYR162
D	ASN163
D	VAL166
D	TYR317
D	ARG327
D	TYR419
D	TYR453
D	ASN457
D	FAD600
D	HOH768
D	HOH1066
D	HOH1082
D	HOH1235
D	HOH1241
D	HOH1294
D	HOH1296
D	HOH1297

site_id	BC2
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD E 600

Chain	Residue
E	GLY14
E	GLY16
E	PRO17
E	THR18
E	ASP38
E	SER39
E	GLY45
E	LEU46
E	ALA47
E	GLY61
E	HIS63
E	GLY240
E	VAL242
E	MET269
E	ARG327
E	GLU373
E	GLY418
E	TYR419
E	GLY446
E	ARG447
E	GLY456
E	ASN457
E	GLN458
E	SER461
E	GDU521
E	HOH522
E	HOH527
E	HOH1009
E	HOH1157

site_id	BC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDU E 521

Chain	Residue
E	ILE65
E	TYR104
E	PHE158
E	MET159
E	TYR162
E	ASN163
E	ARG182
E	VAL183
E	TRP315
E	TYR317
E	ARG327
E	TYR419
E	TYR453
E	ASN457
E	FAD600
E	HOH616

site_id	BC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD F 600

Chain	Residue
F	GLY14
F	GLY16
F	PRO17
F	THR18
F	ASP38
F	SER39
F	GLY45
F	LEU46
F	ALA47
F	GLY61
F	GLY62
F	HIS63
F	GLY240
F	VAL242
F	MET269
F	THR295
F	ARG327
F	GLU373
F	GLY418
F	TYR419
F	GLY446
F	ARG447
F	GLY456
F	ASN457
F	GLN458
F	SER461
F	GDU521
F	HOH569
F	HOH648

site_id	BC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GDU F 521

Chain	Residue
F	ILE65
F	VAL95
F	PHE158
F	MET159
F	TYR162
F	ASN163
F	TYR317
F	ARG327
F	TYR419
F	ARG447
F	TYR453
F	ASN457
F	FAD600
F	HOH1159
F	HOH1292

site_id	BC6
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FAD G 600

Chain	Residue
G	GLY14
G	GLY16
G	PRO17
G	THR18
G	ASP38
G	SER39
G	GLY45
G	LEU46
G	ALA47
G	GLY61
G	HIS63
G	GLY240
G	VAL242
G	MET269
G	THR295
G	ARG327
G	GLU373
G	GLY418
G	TYR419
G	GLY446
G	ARG447
G	GLY456
G	ASN457
G	GLN458
G	SER461
G	GDU521
G	HOH523
G	HOH572
G	HOH723
G	HOH1200
G	HOH1201

site_id	BC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GDU G 521

Chain	Residue
G	ILE65
G	TYR104
G	PHE142
G	PHE158
G	MET159
G	TYR162
G	ASN163
G	VAL166
G	TRP315
G	TYR317
G	ARG327
G	TYR419
G	TYR453
G	ASN457
G	HOH534
G	FAD600
G	HOH797
G	HOH848
G	HOH1196

site_id	BC8
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FDA H 600

Chain	Residue
H	GLY14
H	GLY16
H	PRO17
H	THR18
H	ASP38
H	SER39
H	GLY45
H	LEU46
H	VAL60
H	GLY61
H	GLY62
H	HIS63
H	VAL64
H	GLY240
H	VAL242
H	ARG327
H	GLU373
H	GLY418
H	TYR419
H	GLY446
H	ARG447
H	GLY456
H	ASN457
H	GLN458
H	SER461
H	GDU521
H	HOH525
H	HOH529

site_id	BC9
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDU H 521

Chain	Residue
H	ILE65
H	PHE66
H	VAL95
H	TYR104
H	PHE158
H	MET159
H	TYR162
H	ASN163
H	TRP167
H	ARG182
H	VAL183
H	ASN207
H	TRP315
H	TYR317
H	ARG327
H	TYR419
H	TYR453
H	ASN457
H	FDA600
H	HOH1210
H	HOH1289
H	HOH1293
H	HOH1300

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	53
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	62
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)