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3UIW

Zebrafish Grx2 (APO)

Functional Information from GO Data
ChainGOidnamespacecontents
A0001755biological_processneural crest cell migration
A0001944biological_processvasculature development
A0003147biological_processneural crest cell migration involved in heart formation
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0007417biological_processcentral nervous system development
A0008347biological_processglial cell migration
A0015038molecular_functionglutathione disulfide oxidoreductase activity
A0016491molecular_functionoxidoreductase activity
A0034599biological_processcellular response to oxidative stress
A0046872molecular_functionmetal ion binding
A0051537molecular_function2 iron, 2 sulfur cluster binding
A0060914biological_processheart formation
B0001755biological_processneural crest cell migration
B0001944biological_processvasculature development
B0003147biological_processneural crest cell migration involved in heart formation
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0007417biological_processcentral nervous system development
B0008347biological_processglial cell migration
B0015038molecular_functionglutathione disulfide oxidoreductase activity
B0016491molecular_functionoxidoreductase activity
B0034599biological_processcellular response to oxidative stress
B0046872molecular_functionmetal ion binding
B0051537molecular_function2 iron, 2 sulfur cluster binding
B0060914biological_processheart formation
Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE GSH A 201
ChainResidue
ALYS34
AGLY93
AGLY94
ASER95
AHOH301
AHOH304
AHOH323
ACYS37
APRO38
ATYR39
ATYR39
AGLN69
ATHR80
AVAL81
APRO82

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 202
ChainResidue
ASER26
ACYS28
ACYS116
ACYS117
AHOH333
AHOH334

site_idAC3
Number of Residues11
DetailsBINDING SITE FOR RESIDUE GSH B 201
ChainResidue
BLYS34
BCYS37
BPRO38
BTYR39
BTYR39
BGLN69
BTHR80
BVAL81
BGLY94
BSER95
BASP96

Functional Information from PROSITE/UniProt
site_idPS00195
Number of Residues16
DetailsGLUTAREDOXIN_1 Glutaredoxin active site. IFskttCPYCkmAkg.V
ChainResidueDetails
AILE31-VAL46

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PDB entries from 2024-07-24

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