Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 101 |
| Chain | Residue |
| A | LYS43 |
| C | LYS7 |
| D | ARG57 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 102 |
| Chain | Residue |
| A | LYS43 |
| A | LYS45 |
| A | MET46 |
| D | TRP42 |
| D | HOH202 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE 2NC C 101 |
| Chain | Residue |
| C | GLY27 |
| C | ALA28 |
| C | ASP29 |
| C | ASN30 |
| C | ILE32 |
| C | GLY48 |
| C | ILE50 |
| C | PRO81 |
| C | HOH201 |
| C | HOH213 |
| C | HOH214 |
| D | ASP25 |
| D | GLY27 |
| D | ALA28 |
| D | ASP29 |
| D | ASN30 |
| D | ILE32 |
| D | GLY48 |
| D | ILE50 |
| D | THR80 |
| D | VAL82 |
| D | HOH204 |
| C | ASP25 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 102 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 101 |
| Chain | Residue |
| A | ARG8 |
| A | PHE53 |
| D | PRO44 |
| D | LYS45 |
| D | MET46 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADNTIF |
| Chain | Residue | Details |
| A | ALA22-PHE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| C | ASP25 | |
| D | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
| C | PHE99 | |
| D | PHE99 | |
