3UGX
Crystal Structure of Visual Arrestin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001664 | molecular_function | G protein-coupled receptor binding |
| A | 0001750 | cellular_component | photoreceptor outer segment |
| A | 0001917 | cellular_component | photoreceptor inner segment |
| A | 0002031 | biological_process | G protein-coupled receptor internalization |
| A | 0005829 | cellular_component | cytosol |
| A | 0007165 | biological_process | signal transduction |
| A | 0016020 | cellular_component | membrane |
| A | 0042995 | cellular_component | cell projection |
| B | 0001664 | molecular_function | G protein-coupled receptor binding |
| B | 0001750 | cellular_component | photoreceptor outer segment |
| B | 0001917 | cellular_component | photoreceptor inner segment |
| B | 0002031 | biological_process | G protein-coupled receptor internalization |
| B | 0005829 | cellular_component | cytosol |
| B | 0007165 | biological_process | signal transduction |
| B | 0016020 | cellular_component | membrane |
| B | 0042995 | cellular_component | cell projection |
| C | 0001664 | molecular_function | G protein-coupled receptor binding |
| C | 0001750 | cellular_component | photoreceptor outer segment |
| C | 0001917 | cellular_component | photoreceptor inner segment |
| C | 0002031 | biological_process | G protein-coupled receptor internalization |
| C | 0005829 | cellular_component | cytosol |
| C | 0007165 | biological_process | signal transduction |
| C | 0016020 | cellular_component | membrane |
| C | 0042995 | cellular_component | cell projection |
| D | 0001664 | molecular_function | G protein-coupled receptor binding |
| D | 0001750 | cellular_component | photoreceptor outer segment |
| D | 0001917 | cellular_component | photoreceptor inner segment |
| D | 0002031 | biological_process | G protein-coupled receptor internalization |
| D | 0005829 | cellular_component | cytosol |
| D | 0007165 | biological_process | signal transduction |
| D | 0016020 | cellular_component | membrane |
| D | 0042995 | cellular_component | cell projection |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PTD A 405 |
| Chain | Residue |
| A | ASP19 |
| A | LYS55 |
| A | HIS155 |
| A | MET198 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PTD A 406 |
| Chain | Residue |
| A | TYR58 |
| A | GLN87 |
| C | GLN87 |
| C | PHE152 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PTD A 407 |
| Chain | Residue |
| A | TYR250 |
| A | SER252 |
| A | PTD412 |
| A | VAL248 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PTD A 408 |
| Chain | Residue |
| A | THR258 |
| A | ALA261 |
| A | ASN286 |
| A | ASN287 |
| A | HOH430 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PTD A 409 |
| Chain | Residue |
| A | LYS14 |
| A | TYR25 |
| A | PHE377 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PTD A 410 |
| Chain | Residue |
| A | PRO127 |
| A | CYS128 |
| A | VAL130 |
| A | GLN178 |
| A | SER308 |
| A | SER309 |
| A | THR310 |
| A | ILE311 |
| A | ILE323 |
| A | HOH436 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PTD A 411 |
| Chain | Residue |
| A | TYR125 |
| C | VAL94 |
| C | GLY95 |
| C | ALA96 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PTD A 412 |
| Chain | Residue |
| A | LYS318 |
| A | LEU324 |
| A | PTD407 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 413 |
| Chain | Residue |
| A | SER199 |
| A | GLU231 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 414 |
| Chain | Residue |
| A | TYR84 |
| A | PHE85 |
| C | VAL88 |
| C | GLN89 |
| C | VAL94 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 415 |
| Chain | Residue |
| A | LYS267 |
| B | PHE197 |
| B | ASP200 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD B 405 |
| Chain | Residue |
| B | ARG66 |
| B | GLU70 |
| B | MET131 |
| B | CYS143 |
| B | ASP146 |
| B | HOH435 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PTD B 406 |
| Chain | Residue |
| B | TYR67 |
| B | TYR250 |
| B | SER251 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PTD B 407 |
| Chain | Residue |
| B | LYS318 |
| B | LEU324 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 408 |
| Chain | Residue |
| A | VAL159 |
| B | GLN195 |
| B | HOH411 |
| B | HOH426 |
| B | HOH431 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 409 |
| Chain | Residue |
| A | ASN271 |
| A | SER272 |
| A | SER273 |
| B | GLU350 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PTD C 405 |
| Chain | Residue |
| C | TYR250 |
| C | SER251 |
| C | SER252 |
| site_id | BC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PTD C 406 |
| Chain | Residue |
| B | ASP73 |
| B | VAL74 |
| B | GLY76 |
| C | GLN187 |
| C | PRO188 |
| C | ARG189 |
| C | GLU350 |
| C | PRO352 |
| C | HOH455 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PTD C 407 |
| Chain | Residue |
| C | GLU212 |
| C | THR310 |
| C | VAL325 |
| C | SER326 |
| C | PRO352 |
| C | PHE353 |
| C | ARG354 |
| C | HOH412 |
| site_id | CC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K C 408 |
| Chain | Residue |
| D | GLU350 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 409 |
| Chain | Residue |
| A | GLU160 |
| A | ASP162 |
| C | LYS150 |
| C | ILE164 |
| C | LYS166 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 410 |
| Chain | Residue |
| A | VAL88 |
| A | GLN89 |
| A | VAL94 |
| C | TYR84 |
| C | PHE85 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 411 |
| Chain | Residue |
| C | THR275 |
| D | GLU346 |
| D | ALA348 |
| C | LEU274 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD D 405 |
| Chain | Residue |
| D | ARG66 |
| D | CYS143 |
| D | ASP146 |
| D | HOH430 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD D 406 |
| Chain | Residue |
| D | PRO127 |
| D | CYS128 |
| D | VAL130 |
| D | THR310 |
| D | ILE323 |
| D | HOH432 |
| D | HOH443 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PTD D 407 |
| Chain | Residue |
| D | LYS318 |
| D | LEU324 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 408 |
| Chain | Residue |
| D | GLN187 |
| D | LYS211 |
| D | ILE213 |
| D | TYR215 |
| D | GLU218 |
Functional Information from PROSITE/UniProt
| site_id | PS00295 |
| Number of Residues | 19 |
| Details | ARRESTINS Arrestins signature. FRYGqEDiDVMGLsFrRDL |
| Chain | Residue | Details |
| A | PHE65-LEU83 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylmethionine; partial => ECO:0000269|PubMed:3478675 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| C | MET1 | |
| D | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P15887 |
| Chain | Residue | Details |
| A | THR230 | |
| B | THR230 | |
| C | THR230 | |
| D | THR230 |
