Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3UG3

Crystal structure of alpha-L-arabinofuranosidase from Thermotoga maritima ligand free form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046373	biological_process	L-arabinose metabolic process
A	0046556	molecular_function	alpha-L-arabinofuranosidase activity
B	0000272	biological_process	polysaccharide catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0046373	biological_process	L-arabinose metabolic process
B	0046556	molecular_function	alpha-L-arabinofuranosidase activity
C	0000272	biological_process	polysaccharide catabolic process
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0046373	biological_process	L-arabinose metabolic process
C	0046556	molecular_function	alpha-L-arabinofuranosidase activity
D	0000272	biological_process	polysaccharide catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0046373	biological_process	L-arabinose metabolic process
D	0046556	molecular_function	alpha-L-arabinofuranosidase activity
E	0000272	biological_process	polysaccharide catabolic process
E	0016787	molecular_function	hydrolase activity
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0046373	biological_process	L-arabinose metabolic process
E	0046556	molecular_function	alpha-L-arabinofuranosidase activity
F	0000272	biological_process	polysaccharide catabolic process
F	0016787	molecular_function	hydrolase activity
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0046373	biological_process	L-arabinose metabolic process
F	0046556	molecular_function	alpha-L-arabinofuranosidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TRS A 485

Chain	Residue
A	ASN75
B	HOH545
A	ARG91
A	PHE92
A	HOH507
A	HOH2108
A	HOH2109
B	ASP132
B	HIS136
B	HOH532

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 486

Chain	Residue
A	TYR237
A	GLU281
A	TRP285
A	GLN326
A	HOH2102
A	HOH2104
A	HOH2382

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 487

Chain	Residue
A	GLU172
A	TRP177
A	TYR237
A	HOH924
A	HOH2104

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 488

Chain	Residue
A	HIS235
A	PHE236
A	TYR237
A	PHE378
A	HOH1248

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 489

Chain	Residue
A	ARG189
A	GLU193
A	HOH630
A	HOH2090
C	GLY180
C	HIS181

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 490

Chain	Residue
A	LYS314
A	VAL362
A	LYS363
A	THR364
A	HOH1357

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 491

Chain	Residue
A	VAL200
C	PHE92

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 492

Chain	Residue
A	TYR371
A	HOH1425

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 494

Chain	Residue
A	GLU255
D	LYS261
D	LYS262

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 495

Chain	Residue
A	GLY180
A	HIS181
A	HOH1283
B	ARG189
B	GLU193

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 496

Chain	Residue
A	HOH1577
A	HOH2347
A	HOH2348
E	ASP464
E	HOH1323

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS B 485

Chain	Residue
B	ASN75
B	ARG91
B	PHE92
B	HOH698
B	HOH894
B	HOH2155
C	ASP132
C	LEU135
C	HIS136
C	HOH510
C	HOH2153

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO B 486

Chain	Residue
B	TRP96
B	TYR237
B	GLU281
B	GLN326
B	LEU331
B	HOH731
B	HOH2165
B	HOH2167

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 487

Chain	Residue
B	GLU172
B	TRP177
B	TYR237
B	HOH731
B	HOH1023

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 488

Chain	Residue
B	HIS235
B	TYR237
B	PHE378
B	HOH1364

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 489

Chain	Residue
B	LYS314
B	LEU361
B	VAL362
B	LYS363
B	THR364
B	HOH1367

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 490

Chain	Residue
B	ASN142
B	LYS144
B	PHE201
B	HOH2175

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 492

Chain	Residue
B	VAL200
B	HOH1003

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 493

Chain	Residue
C	TRP197
B	LEU94
B	ALA95
B	GLN97
B	TRP177

site_id	CC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TRS C 485

Chain	Residue
A	ASP132
A	HIS136
A	HOH597
A	HOH618
C	ASN75
C	ARG91
C	PHE92
C	HOH514
C	HOH542
C	HOH590

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 486

Chain	Residue
C	TYR237
C	GLU281
C	TRP285
C	GLN326
C	HOH512
C	HOH1734
C	HOH2196

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 487

Chain	Residue
C	GLU172
C	TRP177
C	TYR237
C	HOH987
C	HOH1734
C	HOH2196

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 488

Chain	Residue
C	HIS235
C	PHE236
C	TYR237
C	PHE378
C	MET382
C	HOH1703

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 489

Chain	Residue
B	GLY180
B	HIS181
C	ARG189
C	GLU193
C	HOH796

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 490

Chain	Residue
C	VAL362
C	LYS363
C	THR364
C	HOH1116

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 491

Chain	Residue
C	ASN142
C	LYS144
C	PHE201
C	ASP202

site_id	CC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO C 492

Chain	Residue
C	TYR371

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 493

Chain	Residue
C	GLU255
C	HOH910
F	LYS261
F	LYS262

site_id	DC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 485

Chain	Residue
D	TYR237
D	GLU281
D	TRP285
D	GLN326
D	HOH500
D	HOH830
D	HOH1933

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 486

Chain	Residue
D	GLU172
D	TRP177
D	TYR237
D	HOH1403
D	HOH1933

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 487

Chain	Residue
D	HIS235
D	PHE236
D	TYR237
D	PHE378
D	HOH1079
D	HOH1574

site_id	DC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 488

Chain	Residue
D	ARG189
D	GLU193
D	HOH839
D	HOH1709
E	GLY180
E	HIS181

site_id	DC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 489

Chain	Residue
D	VAL13
D	LYS314
D	VAL362
D	LYS363
D	THR364

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO D 490

Chain	Residue
D	ASN142
D	LYS144
D	PHE201

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO D 491

Chain	Residue
D	TYR244

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO D 492

Chain	Residue
D	TRP197
D	VAL200
D	HOH1017
E	TRP177

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 493

Chain	Residue
A	LYS261
D	GLU255

site_id	EC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS D 494

Chain	Residue
D	ASN75
D	ARG91
D	PHE92
D	HOH509
D	HOH516
D	HOH669
D	HOH795
F	ASP132
F	LEU135
F	HIS136
F	HOH562

site_id	EC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE TRS E 485

Chain	Residue
D	ASP132
D	HIS136
D	HOH2250
D	HOH2251
E	ASN75
E	PHE92
E	HOH603
E	HOH2253
E	HOH2286

site_id	EC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 486

Chain	Residue
E	TYR237
E	GLU281
E	TRP285
E	GLN326
E	LEU331
E	HOH543
E	HOH2271
E	HOH2273

site_id	EC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 487

Chain	Residue
E	GLU172
E	TRP177
E	TYR237
E	HOH543
E	HOH944

site_id	EC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 488

Chain	Residue
E	HIS235
E	PHE236
E	TYR237
E	PHE378
E	HOH1627

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 489

Chain	Residue
E	ARG189
E	GLU193
E	HOH781
F	GLY180
F	HIS181

site_id	EC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO E 490

Chain	Residue
E	LYS314
E	LYS363
E	THR364

site_id	EC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 491

Chain	Residue
E	ASN142
E	LYS144
E	PHE201
E	ASP202
E	HOH598

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO E 492

Chain	Residue
E	TYR244
E	TYR371

site_id	FC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO E 493

Chain	Residue
E	VAL200
E	HOH1131
F	TRP177

site_id	FC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS F 485

Chain	Residue
E	ASP132
E	LEU135
E	HIS136
E	HOH560
F	ASN75
F	ARG91
F	PHE92
F	HOH576
F	HOH848
F	HOH2302
F	HOH2303

site_id	FC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO F 486

Chain	Residue
F	LEU28
F	TYR237
F	GLU281
F	TRP285
F	GLN326
F	HOH807
F	HOH2312
F	HOH2313

site_id	FC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO F 487

Chain	Residue
F	GLU172
F	TRP177
F	TYR237
F	HOH642
F	HOH807

site_id	FC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 488

Chain	Residue
F	HIS235
F	PHE236
F	TYR237
F	PHE378
F	MET382
F	HOH1957

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO F 489

Chain	Residue
D	GLY180
D	HIS181
F	ARG189
F	GLU193

site_id	FC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO F 490

Chain	Residue
F	LYS314
F	LEU361
F	VAL362
F	LYS363
F	THR364

site_id	FC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 491

Chain	Residue
F	ASN142
F	LYS144
F	PHE201
F	ASP202
F	HOH684
F	HOH961

site_id	GC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO F 492

Chain	Residue
F	TYR244
F	TYR371
F	HOH1546
F	HOH1548

site_id	GC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO F 493

Chain	Residue
F	HOH1497

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)