3U94

Crystal structure of the GluK3 ligand binding domain complex with glutamate and zinc: P21212 form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane
C	0015276	molecular_function	ligand-gated monoatomic ion channel activity
C	0016020	cellular_component	membrane
D	0015276	molecular_function	ligand-gated monoatomic ion channel activity
D	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GLU A 258

Chain	Residue
A	TYR61
A	TYR215
A	HOH265
A	HOH290
A	HOH291
A	HOH302
A	PRO88
A	LEU89
A	THR90
A	ARG95
A	GLY140
A	ALA141
A	THR142
A	GLU189

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU B 258

Chain	Residue
B	TYR61
B	PRO88
B	LEU89
B	THR90
B	ARG95
B	GLY140
B	ALA141
B	THR142
B	GLU189
B	HOH281
B	HOH283
B	HOH300
B	HOH330

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GLU C 258

Chain	Residue
C	TYR61
C	PRO88
C	THR90
C	ARG95
C	GLY140
C	ALA141
C	THR142
C	GLU189
C	HOH268
C	HOH271
C	HOH296
C	HOH324

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GLU D 258

Chain	Residue
D	TYR61
D	PRO88
D	THR90
D	ARG95
D	GLY140
D	ALA141
D	THR142
D	GLU189
D	HOH273
D	HOH274
D	HOH278
D	HOH292

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 259

Chain	Residue
A	HIS243
A	GLU247
B	GLU194

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 259

Chain	Residue
A	GLU194
A	LYS246
B	HIS243
B	GLU247
B	HOH297

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 259

Chain	Residue
B	HIS93
B	GLU96
C	ASP240
C	HIS243

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 259

Chain	Residue
A	HIS93
A	GLU96
D	ASP240
D	HIS243

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN D 260

Chain	Residue
B	GLU238
D	GLU238
D	HOH650

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 260

Chain	Residue
A	HIS80
C	HIS93

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 261

Chain	Residue
A	HIS45
A	HOH688
A	HOH689

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 260

Chain	Residue
A	GLU238
C	GLU238

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 260

Chain	Residue
B	HIS80
B	HOH298
B	HOH651
D	HIS93
D	LYS97

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 261

Chain	Residue
C	GLU42
C	LYS241
C	HOH652
D	HIS45

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 261

Chain	Residue
C	HIS45
C	HOH653
D	GLU42
D	LYS241

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 262

Chain	Residue
C	HIS80
C	HIS80

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN D 262

Chain	Residue
D	HIS80
D	HIS80
D	HOH681

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 263

Chain	Residue
D	ARG20
D	ARG24

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 261

Chain	Residue
B	HIS45
B	HOH630

---

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 263

Chain	Residue
C	ARG20
C	SER22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21907808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3S9E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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