3U93

Crystal structure of the GluK3 ligand binding domain complex with glutamate and zinc: P2221 form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU A 258

Chain	Residue
A	TYR61
A	HOH271
A	HOH276
A	HOH322
A	HOH324
A	PRO88
A	LEU89
A	THR90
A	ARG95
A	GLY140
A	ALA141
A	THR142
A	GLU189

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 259

Chain	Residue
A	GLU194
A	HIS243
A	LYS246
A	GLU247

---

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU B 258

Chain	Residue
B	TYR61
B	PRO88
B	LEU89
B	THR90
B	ARG95
B	GLY140
B	ALA141
B	THR142
B	GLU189
B	HOH267
B	HOH283
B	HOH296
B	HOH317

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 259

Chain	Residue
A	HIS93
A	GLU96
B	ASP240
B	HIS243

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 260

Chain	Residue
A	HIS80
B	HIS93
B	LYS97

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 261

Chain	Residue
B	GLU42
B	HIS45
B	LYS241
B	HOH362

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 262

Chain	Residue
B	HIS80
B	HIS80

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 263

Chain	Residue
B	ARG31
B	LEU55

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 264

Chain	Residue
B	ARG24

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21907808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3S9E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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