3U1S

Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 L 215

Chain	Residue
L	ARG39
L	ARG45

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 L 216

Chain	Residue
L	ARG54
L	HOH221
L	HOH258
L	HOH279

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 217

Chain	Residue
L	LYS207
L	HOH315
H	SER133
H	LYS134
L	LYS188

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 218

Chain	Residue
L	GLY41
L	GLN42
L	THR43
L	ARG45
L	HOH294

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL L 219

Chain	Residue
L	LEU9
L	PHE10

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 223

Chain	Residue
H	ARG71
H	ASP72
H	SER73
H	GLY74
H	ALA75

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site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 H 224

Chain	Residue
H	HIS52
H	HIS52
H	GLU52
H	GLU52
H	LYS97
H	LYS97
H	ARG99
H	ARG99
H	HOH305
H	HOH305

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR199-HIS205
L	TYR192-HIS198

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