3U1Q
Crystal Structure of M. tuberculosis LD-transpeptidase type 2 with 2-Mercaptoethanol
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BME A 501 |
| Chain | Residue |
| A | HIS336 |
| A | SER351 |
| A | HIS352 |
| A | CYS354 |
| A | ASN356 |
| A | HOH674 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME A 502 |
| Chain | Residue |
| A | SER331 |
| A | GLY332 |
| A | HOH614 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 503 |
| Chain | Residue |
| A | SER306 |
| A | PRO311 |
| A | VAL312 |
| A | ASN313 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 504 |
| Chain | Residue |
| A | HIS214 |
| A | PHE215 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME B 501 |
| Chain | Residue |
| B | SER351 |
| B | HIS352 |
| B | CYS354 |
| B | HOH689 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME B 502 |
| Chain | Residue |
| B | SER331 |
| B | GLY332 |
| B | HIS352 |
| B | GLY353 |
| B | CYS354 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 503 |
| Chain | Residue |
| A | SER314 |
| A | PRO315 |
| A | HOH663 |
| B | SER284 |
| B | VAL310 |
| B | SER314 |
| B | PRO315 |
| B | ASN316 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 504 |
| Chain | Residue |
| B | THR256 |
| B | ASP258 |
| B | THR261 |
| B | ILE263 |
| B | THR265 |
| B | ARG267 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 505 |
| Chain | Residue |
| B | GLY387 |
| B | ILE388 |
| B | GLN400 |
| B | HOH637 |
| B | HOH702 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG B 506 |
| Chain | Residue |
| B | VAL196 |
| B | PRO212 |
| B | GLU213 |
| B | HIS214 |
| B | PHE215 |
| B | TRP216 |
| B | LYS217 |
| B | THR220 |
| B | HOH617 |
| B | HOH686 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 250 |
| Details | Domain: {"description":"L,D-TPase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Binds to carbapenem drug (covalent)","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
