3U0Z
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0005249 | molecular_function | voltage-gated potassium channel activity |
| A | 0005887 | cellular_component | integral component of plasma membrane |
| A | 0030552 | molecular_function | cAMP binding |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005249 | molecular_function | voltage-gated potassium channel activity |
| B | 0005887 | cellular_component | integral component of plasma membrane |
| B | 0030552 | molecular_function | cAMP binding |
| B | 0035725 | biological_process | sodium ion transmembrane transport |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE CMP A 646 |
| 鎖名 | 残基 |
| A | VAL511 |
| A | ARG579 |
| A | ARG582 |
| A | PHE527 |
| A | GLY528 |
| A | GLU529 |
| A | ILE530 |
| A | CYS531 |
| A | ARG538 |
| A | THR539 |
| A | ALA540 |
| site_id | AC2 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE CMP B 646 |
| 鎖名 | 残基 |
| B | VAL511 |
| B | PHE527 |
| B | GLY528 |
| B | GLU529 |
| B | ILE530 |
| B | CYS531 |
| B | ARG538 |
| B | THR539 |
| B | ALA540 |
| B | ARG579 |
| B | ARG582 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00888 |
| 残基数 | 17 |
| 詳細 | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGAvGKkMYFIqhG |
| 鎖名 | 残基 | 詳細 |
| A | ILE491-GLY507 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 6 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:22006928, ECO:0007744|PDB:3U0Z |
| 鎖名 | 残基 | 詳細 |
| A | GLY528 | |
| A | ARG538 | |
| A | ARG579 | |
| B | GLY528 | |
| B | ARG538 | |
| B | ARG579 |
