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3U0V

Crystal Structure Analysis of human LYPLAL1

Functional Information from GO Data
ChainGOidnamespacecontents
A0004622molecular_functionphosphatidylcholine lysophospholipase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0008474molecular_functionpalmitoyl-(protein) hydrolase activity
A0016298molecular_functionlipase activity
A0016787molecular_functionhydrolase activity
A0016788molecular_functionhydrolase activity, acting on ester bonds
A0042997biological_processnegative regulation of Golgi to plasma membrane protein transport
A0098734biological_processmacromolecule depalmitoylation
A0160049biological_processnegative regulation of cGAS/STING signaling pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsActive site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"O75608","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsActive site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"37802025","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

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PDB entries from 2025-12-10

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