3U0V

Crystal Structure Analysis of human LYPLAL1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004622	molecular_function	lysophospholipase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008150	biological_process	biological_process
A	0008474	molecular_function	palmitoyl-(protein) hydrolase activity
A	0016298	molecular_function	lipase activity
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	0098734	biological_process	macromolecule depalmitoylation
A	0160049	biological_process	negative regulation of cGAS/STING signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:O75608

Chain	Residue	Details
A	SER124

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Charge relay system => ECO:0000305|PubMed:37802025

Chain	Residue	Details
A	ASP179
A	HIS211

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.5, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA2

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