Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3U0G

Crystal structure of branched-chain amino acid aminotransferase from burkholderia pseudomallei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid transaminase activity
A	0005829	cellular_component	cytosol
A	0006532	biological_process	aspartate biosynthetic process
A	0008483	molecular_function	transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	valine biosynthetic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
A	0052654	molecular_function	L-leucine transaminase activity
A	0052655	molecular_function	L-valine transaminase activity
A	0052656	molecular_function	L-isoleucine transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid transaminase activity
B	0005829	cellular_component	cytosol
B	0006532	biological_process	aspartate biosynthetic process
B	0008483	molecular_function	transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	valine biosynthetic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
B	0052654	molecular_function	L-leucine transaminase activity
B	0052655	molecular_function	L-valine transaminase activity
B	0052656	molecular_function	L-isoleucine transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid transaminase activity
C	0005829	cellular_component	cytosol
C	0006532	biological_process	aspartate biosynthetic process
C	0008483	molecular_function	transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	valine biosynthetic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
C	0052654	molecular_function	L-leucine transaminase activity
C	0052655	molecular_function	L-valine transaminase activity
C	0052656	molecular_function	L-isoleucine transaminase activity
D	0003824	molecular_function	catalytic activity
D	0004084	molecular_function	branched-chain-amino-acid transaminase activity
D	0005829	cellular_component	cytosol
D	0006532	biological_process	aspartate biosynthetic process
D	0008483	molecular_function	transaminase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009081	biological_process	branched-chain amino acid metabolic process
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009098	biological_process	L-leucine biosynthetic process
D	0009099	biological_process	valine biosynthetic process
D	0046394	biological_process	carboxylic acid biosynthetic process
D	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
D	0052654	molecular_function	L-leucine transaminase activity
D	0052655	molecular_function	L-valine transaminase activity
D	0052656	molecular_function	L-isoleucine transaminase activity
E	0003824	molecular_function	catalytic activity
E	0004084	molecular_function	branched-chain-amino-acid transaminase activity
E	0005829	cellular_component	cytosol
E	0006532	biological_process	aspartate biosynthetic process
E	0008483	molecular_function	transaminase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009081	biological_process	branched-chain amino acid metabolic process
E	0009082	biological_process	branched-chain amino acid biosynthetic process
E	0009097	biological_process	isoleucine biosynthetic process
E	0009098	biological_process	L-leucine biosynthetic process
E	0009099	biological_process	valine biosynthetic process
E	0046394	biological_process	carboxylic acid biosynthetic process
E	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
E	0052654	molecular_function	L-leucine transaminase activity
E	0052655	molecular_function	L-valine transaminase activity
E	0052656	molecular_function	L-isoleucine transaminase activity
F	0003824	molecular_function	catalytic activity
F	0004084	molecular_function	branched-chain-amino-acid transaminase activity
F	0005829	cellular_component	cytosol
F	0006532	biological_process	aspartate biosynthetic process
F	0008483	molecular_function	transaminase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009081	biological_process	branched-chain amino acid metabolic process
F	0009082	biological_process	branched-chain amino acid biosynthetic process
F	0009097	biological_process	isoleucine biosynthetic process
F	0009098	biological_process	L-leucine biosynthetic process
F	0009099	biological_process	valine biosynthetic process
F	0046394	biological_process	carboxylic acid biosynthetic process
F	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
F	0052654	molecular_function	L-leucine transaminase activity
F	0052655	molecular_function	L-valine transaminase activity
F	0052656	molecular_function	L-isoleucine transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C 308

Chain	Residue
C	ARG62
C	GLY220
C	ILE221
C	THR222
C	GLY257
C	THR258
C	HOH329
C	HOH359

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 F 308

Chain	Residue
F	GLY220
F	ILE221
F	THR222
F	GLY257
F	THR258
F	HOH538
F	HOH539
F	ARG62

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 308

Chain	Residue
B	ARG62
B	GLY220
B	ILE221
B	THR222
B	GLY257
B	THR258
B	HOH364
B	HOH451

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 308

Chain	Residue
A	ARG62
A	GLY220
A	ILE221
A	THR222
A	GLY257
A	THR258
A	HOH365
A	HOH436

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D 308

Chain	Residue
D	ARG62
D	GLY220
D	ILE221
D	THR222
D	THR258

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 E 308

Chain	Residue
E	ARG62
E	LEU218
E	GLY220
E	ILE221
E	THR222
E	THR258
E	HOH528

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL F 309

Chain	Residue
D	ASP219
F	ARG206
F	GLU246
F	HOH552

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 309

Chain	Residue
C	LEU203
C	TYR210
C	GLU246
C	HOH339
E	LEU214

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 309

Chain	Residue
A	LEU214
E	LEU203
E	ASN205
E	ARG206
E	GLU246
E	HOH326
E	HOH611

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 310

Chain	Residue
F	TYR98

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 309

Chain	Residue
B	TYR98

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 309

Chain	Residue
A	TYR98

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 310

Chain	Residue
C	TYR98

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 309

Chain	Residue
D	TYR98

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E 310

Chain	Residue
E	TYR98

Functional Information from PROSITE/UniProt

site_id	PS00770
Number of Residues	29
Details	AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EgSgeNFFlvnrgk......LyTpdlasc..LdGItR

Chain	Residue	Details
A	GLU195-ARG223

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)