3TZE
Crystal structure of a tryptophanyl-tRNA synthetase from Encephalitozoon cuniculi bound to tryptophan
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004830 | molecular_function | tryptophan-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006436 | biological_process | tryptophanyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004830 | molecular_function | tryptophan-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006436 | biological_process | tryptophanyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRP A 386 |
| Chain | Residue |
| A | TYR84 |
| A | THR85 |
| A | GLY86 |
| A | GLN119 |
| A | THR121 |
| A | GLU124 |
| A | GLU206 |
| A | VAL226 |
| A | GLN232 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 387 |
| Chain | Residue |
| A | SER212 |
| A | PHE215 |
| A | ILE218 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TRP B 386 |
| Chain | Residue |
| B | TYR84 |
| B | GLY86 |
| B | ARG87 |
| B | GLY88 |
| B | GLN119 |
| B | GLU124 |
| B | LYS125 |
| B | GLU206 |
| B | ALA228 |
| B | GLN232 |
| B | PHE236 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K B 387 |
| Chain | Residue |
| B | SER212 |
| B | PHE215 |
| B | ILE218 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 11 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. Ps.SKtMHIGHT |
| Chain | Residue | Details |
| A | PRO89-THR99 |
