Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE TZG A 261 |
| Chain | Residue |
| A | TYR58 |
| A | GLU190 |
| A | MET193 |
| A | TYR217 |
| A | HOH327 |
| A | HOH377 |
| A | HOH394 |
| A | PRO86 |
| A | LEU87 |
| A | THR88 |
| A | ARG93 |
| A | LEU135 |
| A | SER139 |
| A | THR140 |
| A | LEU189 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 262 |
| Chain | Residue |
| A | LYS141 |
| A | ARG145 |
| A | ARG160 |
| A | HOH438 |
| A | HOH576 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 263 |
| Chain | Residue |
| A | LYS57 |
| A | ALA60 |
| A | ASN69 |
| A | SER137 |
| A | GLY138 |
| A | HOH336 |
| A | HOH337 |
| A | HOH393 |
| A | HOH479 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 264 |
| Chain | Residue |
| A | LYS79 |
| A | LYS113 |
| A | ARG179 |
| A | HOH528 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE TZG B 261 |
| Chain | Residue |
| B | TYR58 |
| B | PRO86 |
| B | LEU87 |
| B | THR88 |
| B | ARG93 |
| B | LEU135 |
| B | THR140 |
| B | THR171 |
| B | LEU189 |
| B | GLU190 |
| B | MET193 |
| B | TYR217 |
| B | HOH312 |
| B | HOH368 |
| B | HOH548 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 262 |
| Chain | Residue |
| B | HIS43 |
| B | LYS237 |
| B | GLN241 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO86 | |
| B | SER139 | |
| B | THR140 | |
| B | GLU190 | |
| A | THR88 | |
| A | ARG93 | |
| A | SER139 | |
| A | THR140 | |
| A | GLU190 | |
| B | PRO86 | |
| B | THR88 | |
| B | ARG93 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG61 | |
| A | ARG145 | |
| A | LYS237 | |
| B | ARG61 | |
| B | ARG145 | |
| B | LYS237 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE118 | |
| B | ILE118 | |
| Chain | Residue | Details |
| A | SER147 | |
| B | SER147 | |
| Chain | Residue | Details |
| A | SER181 | |
| B | SER181 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN0 | |
| B | ASN0 | |
