3TWK
Crystal structure of arabidopsis thaliana FPG
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008534 | molecular_function | oxidized purine nucleobase lesion DNA N-glycosylase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0019104 | molecular_function | DNA N-glycosylase activity |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003684 | molecular_function | damaged DNA binding |
| B | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006284 | biological_process | base-excision repair |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008534 | molecular_function | oxidized purine nucleobase lesion DNA N-glycosylase activity |
| B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| B | 0019104 | molecular_function | DNA N-glycosylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | PRO2 |
| A | MSE78 |
| A | HOH468 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | HOH607 |
| A | SER68 |
| A | SER205 |
| A | SER206 |
| A | LEU207 |
| A | SER208 |
| A | HOH606 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Schiff-base intermediate with DNA => ECO:0000255|PROSITE-ProRule:PRU00392 |
| Chain | Residue | Details |
| A | PRO2 | |
| B | PRO2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU00392 |
| Chain | Residue | Details |
| A | GLU3 | |
| B | GLU3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor; for beta-elimination activity => ECO:0000255|PROSITE-ProRule:PRU00392 |
| Chain | Residue | Details |
| A | LYS60 | |
| B | LYS60 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22789755 |
| Chain | Residue | Details |
| A | TYR107 | |
| A | LYS167 | |
| A | ASN186 | |
| B | TYR107 | |
| B | LYS167 | |
| B | ASN186 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG126 | |
| B | ARG126 |
