3TVK
Diguanylate cyclase domain of DgcZ
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE C2E A 501 |
| Chain | Residue |
| A | PHE169 |
| A | GLU208 |
| A | HOH641 |
| A | HOH732 |
| A | LYS170 |
| A | ASN173 |
| A | HIS178 |
| A | GLY181 |
| A | ASP182 |
| A | LEU185 |
| A | ARG204 |
| A | GLY207 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE C2E A 502 |
| Chain | Residue |
| A | SER194 |
| A | TRP195 |
| A | THR196 |
| A | ARG197 |
| A | ASP198 |
| A | ARG228 |
| A | ASP270 |
| A | ARG271 |
| A | TYR274 |
| A | GLU275 |
| A | GLN278 |
| A | ILE293 |
| A | C2E503 |
| A | MG504 |
| A | HOH615 |
| A | HOH620 |
| A | HOH636 |
| A | HOH678 |
| A | HOH680 |
| A | HOH685 |
| A | HOH714 |
| A | HOH717 |
| A | HOH726 |
| A | HOH729 |
| A | HOH734 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C2E A 503 |
| Chain | Residue |
| A | ALA126 |
| A | ARG197 |
| A | GLU200 |
| A | LYS215 |
| A | GLU221 |
| A | ARG224 |
| A | ALA225 |
| A | ARG228 |
| A | ARG271 |
| A | C2E502 |
| A | HOH604 |
| A | HOH607 |
| A | HOH609 |
| A | HOH638 |
| A | HOH711 |
| A | HOH727 |
| A | HOH738 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 504 |
| Chain | Residue |
| A | ASP198 |
| A | C2E502 |
| A | HOH678 |
| A | HOH680 |
| A | HOH685 |
| A | HOH723 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TAR A 505 |
| Chain | Residue |
| A | ARG168 |
| A | SER194 |
| A | TRP195 |
| A | HIS236 |
| A | GLY280 |
| A | HOH739 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 132 |
| Details | Domain: {"description":"GGDEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00095","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23769666","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4H54","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23769666","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
