Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003963 | molecular_function | RNA-3'-phosphate cyclase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006396 | biological_process | RNA processing |
| A | 0016874 | molecular_function | ligase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003963 | molecular_function | RNA-3'-phosphate cyclase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006396 | biological_process | RNA processing |
| B | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE AMP A 401 |
| Chain | Residue |
| A | ARG21 |
| A | ASN309 |
| A | HOH428 |
| A | HOH509 |
| A | HOH538 |
| A | HOH565 |
| A | HOH566 |
| A | GLN104 |
| A | SER129 |
| A | ALA130 |
| A | PRO131 |
| A | PHE251 |
| A | TYR284 |
| A | ASP287 |
| A | GLN288 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE AMP B 401 |
| Chain | Residue |
| B | ARG21 |
| B | GLN104 |
| B | SER129 |
| B | ALA130 |
| B | PRO131 |
| B | PHE135 |
| B | PHE251 |
| B | TYR284 |
| B | ASP287 |
| B | GLN288 |
| B | ASN309 |
| B | HOH359 |
| B | HOH389 |
| B | HOH477 |
| B | HOH624 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 801 |
| Chain | Residue |
| B | HIS158 |
| B | LEU197 |
| B | HIS225 |
| B | HOH461 |
| B | HOH537 |
| B | HOH866 |
| B | HOH890 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 802 |
| Chain | Residue |
| A | HIS158 |
| A | LEU197 |
| A | HIS225 |
| A | HOH502 |
| A | HOH526 |
| A | HOH541 |
| A | HOH827 |
| A | HOH828 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 803 |
| Chain | Residue |
| A | GLU14 |
| A | ARG43 |
| A | HOH657 |
| A | HOH805 |
| A | HOH862 |
| A | HOH878 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 804 |
| Chain | Residue |
| B | GLU14 |
| B | ARG43 |
| B | HOH575 |
| B | HOH614 |
| B | HOH823 |
| B | HOH865 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 851 |
| Chain | Residue |
| B | THR125 |
| B | ASP126 |
| B | ALA133 |
| B | HOH728 |
| B | PEG991 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 901 |
| Chain | Residue |
| A | ARG137 |
| A | ARG138 |
| A | ARG193 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 951 |
| Chain | Residue |
| A | GLU207 |
| A | ILE210 |
| A | ALA211 |
| A | HOH678 |
| A | HOH872 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 991 |
| Chain | Residue |
| B | ASP126 |
| B | PRO132 |
| B | ALA133 |
| B | ASP134 |
| B | LEU155 |
| B | HOH666 |
| B | CL851 |
| B | HOH890 |
Functional Information from PROSITE/UniProt
| site_id | PS01287 |
| Number of Residues | 11 |
| Details | RTC RNA 3'-terminal phosphate cyclase signature. HGfyPaGGGvV |
| Chain | Residue | Details |
| A | HIS158-VAL168 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Tele-AMP-histidine intermediate","evidences":[{"source":"PubMed","id":"20399182","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QMH","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20399182","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3KGD","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 882 |
| Chain | Residue | Details |
| A | GLU14 | modifies pKa |
| A | ASN309 | covalent catalysis |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 882 |
| Chain | Residue | Details |
| B | GLU14 | modifies pKa |
| B | ASN309 | covalent catalysis |
