3TPM

Crystal structure of MAL RPEL domain in complex with importin-alpha

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003713	molecular_function	transcription coactivator activity
B	0003785	molecular_function	actin monomer binding
B	0005737	cellular_component	cytoplasm
B	0010735	biological_process	positive regulation of transcription via serum response element binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	Repeat: {"description":"ARM 2"}

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site_id	SWS_FT_FI2
Number of Residues	41
Details	Repeat: {"description":"ARM 3"}

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site_id	SWS_FT_FI3
Number of Residues	44
Details	Repeat: {"description":"ARM 4"}

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site_id	SWS_FT_FI4
Number of Residues	36
Details	Repeat: {"description":"ARM 5"}

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site_id	SWS_FT_FI5
Number of Residues	39
Details	Repeat: {"description":"ARM 6"}

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site_id	SWS_FT_FI6
Number of Residues	39
Details	Repeat: {"description":"ARM 7"}

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site_id	SWS_FT_FI7
Number of Residues	42
Details	Repeat: {"description":"ARM 8"}

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site_id	SWS_FT_FI8
Number of Residues	46
Details	Repeat: {"description":"ARM 9"}

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site_id	SWS_FT_FI9
Number of Residues	39
Details	Repeat: {"description":"ARM 10; atypical"}

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Residue

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site_id	SWS_FT_FI10
Number of Residues	96
Details	Region: {"description":"NLS binding site (major)","evidences":[{"source":"PubMed","id":"10764582","evidenceCode":"ECO:0000269"}]}

Chain

Residue

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site_id	SWS_FT_FI11
Number of Residues	88
Details	Region: {"description":"NLS binding site (minor)","evidences":[{"source":"PubMed","id":"10764582","evidenceCode":"ECO:0000269"}]}

Chain

Residue

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